About Immunoglobulin-like domain-containing receptor 2
Immunoglobulin-like domain-containing receptor 2 (ILDR2) is a protein
from Homo sapiens identified by UniProt accession
Q71H61, 639 residues long.
MolForge cross-references it against 0 known binders and
64 disease associations.
Target properties
| Protein name | Immunoglobulin-like domain-containing receptor 2 |
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| UniProt accession | Q71H61 |
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| Gene | ILDR2 |
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| Organism | Homo sapiens |
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| Length | 639 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (64)
Diseases linked to this target (Open Targets).
- sex hormone-binding globulin measurement · score 0.34
- neutrophil count · score 0.24
- brain measurement · score 0.21
- cortical surface area measurement · score 0.21
- cortical thickness · score 0.17
- neuroimaging measurement · score 0.17
- leukocyte count · score 0.16
- myeloid white cell count · score 0.10
- MODY · score 0.09
- platelet component distribution width · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q71H61-F1 | alphafold | PREDICTED | 56.32 | — |
Amino-acid sequence (639 residues)
MDRVLLRWIS LFWLTAMVEG LQVTVPDKKK VAMLFQPTVL RCHFSTSSHQ PAVVQWKFKS YCQDRMGESL GMSSTRAQSL SKRNLEWDPY LDCLDSRRTV RVVASKQGST VTLGDFYRGR EITIVHDADL QIGKLMWGDS GLYYCIITTP DDLEGKNEDS VELLVLGRTG LLADLLPSFA VEIMPEWVFV GLVLLGVFLF FVLVGICWCQ CCPHSCCCYV RCPCCPDSCC CPQALYEAGK AAKAGYPPSV SGVPGPYSIP SVPLGGAPSS GMLMDKPHPP PLAPSDSTGG SHSVRKGYRI QADKERDSMK VLYYVEKELA QFDPARRMRG RYNNTISELS SLHEEDSNFR QSFHQMRSKQ FPVSGDLESN PDYWSGVMGG SSGASRGPSA MEYNKEDRES FRHSQPRSKS EMLSRKNFAT GVPAVSMDEL AAFADSYGQR PRRADGNSHE ARGGSRFERS ESRAHSGFYQ DDSLEEYYGQ RSRSREPLTD ADRGWAFSPA RRRPAEDAHL PRLVSRTPGT APKYDHSYLG SARERQARPE GASRGGSLET PSKRSAQLGP RSASYYAWSP PGTYKAGSSQ DDQEDASDDA LPPYSELELT RGPSYRGRDL PYHSNSEKKR KKEPAKKTND FPTRMSLVV
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