About La-related protein 4
La-related protein 4 (LARP4) is a protein
from Homo sapiens identified by UniProt accession
Q71RC2, 724 residues long.
MolForge cross-references it against 0 known binders and
24 disease associations.
Target properties
| Protein name | La-related protein 4 |
|---|
| UniProt accession | Q71RC2 |
|---|
| Gene | LARP4 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 724 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (24)
Diseases linked to this target (Open Targets).
- drug use measurement · score 0.23
- neoplasm · score 0.08
- cancer · score 0.06
- hypertension · score 0.06
- Red cell distribution width · score 0.06
- non-small cell lung carcinoma · score 0.04
- colorectal cancer · score 0.03
- neutrophil count · score 0.03
- sex hormone-binding globulin measurement · score 0.02
- glioblastoma multiforme · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q71RC2-F1 | alphafold | PREDICTED | 54.40 | — |
Amino-acid sequence (724 residues)
MLLFVEQVAS KGTGLNPNAK VWQEIAPGNT DATPVTHGTE SSWHEIAATS GAHPEGNAEL SEDICKEYEV MYSSSCETTR NTTGIEESTD GMILGPEDLS YQIYDVSGES NSAVSTEDLK ECLKKQLEFC FSRENLSKDL YLISQMDSDQ FIPIWTVANM EEIKKLTTDP DLILEVLRSS PMVQVDEKGE KVRPSHKRCI VILREIPETT PIEEVKGLFK SENCPKVISC EFAHNSNWYI TFQSDTDAQQ AFKYLREEVK TFQGKPIMAR IKAINTFFAK NGYRLMDSSI YSHPIQTQAQ YASPVFMQPV YNPHQQYSVY SIVPQSWSPN PTPYFETPLA PFPNGSFVNG FNSPGSYKTN AAAMNMGRPF QKNRVKPQFR SSGGSEHSTE GSVSLGDGQL NRYSSRNFPA ERHNPTVTGH QEQTYLQKET STLQVEQNGD YGRGRRTLFR GRRRREDDRI SRPHPSTAES KAPTPKFDLL ASNFPPLPGS SSRMPGELVL ENRMSDVVKG VYKEKDNEEL TISCPVPADE QTECTSAQQL NMSTSSPCAA ELTALSTTQQ EKDLIEDSSV QKDGLNQTTI PVSPPSTTKP SRASTASPCN NNINAATAVA LQEPRKLSYA EVCQKPPKEP SSVLVQPLRE LRSNVVSPTK NEDNGAPENS VEKPHEKPEA RASKDYSGFR GNIIPRGAAG KIREQRRQFS HRAIPQGVTR RNGKEQYVPP RSPK
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