Ribosomal protein eS27-like (RPS27L)

About Ribosomal protein eS27-like

Ribosomal protein eS27-like (RPS27L) is a protein from Homo sapiens identified by UniProt accession Q71UM5, 84 residues long. MolForge cross-references it against 0 known binders and 56 disease associations.

Target properties

Protein name	Ribosomal protein eS27-like
UniProt accession	Q71UM5
Gene	RPS27L
Organism	Homo sapiens
Length	84 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (56)

Diseases linked to this target (Open Targets).

influenza · score 0.46
COVID-19 · score 0.37
severe acute respiratory syndrome · score 0.37
serum metabolite measurement · score 0.28
neurodegenerative disease · score 0.28
systolic blood pressure · score 0.21
blood metabolite measurement · score 0.20
metabolite measurement · score 0.20
pulse pressure measurement · score 0.12
mean platelet volume · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q71UM5-F1	alphafold	PREDICTED	92.94	—

Amino-acid sequence (84 residues)

MPLARDLLHP SLEEEKKKHK KKRLVQSPNS YFMDVKCPGC YKITTVFSHA QTVVLCVGCS TVLCQPTGGK ARLTEGCSFR RKQH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards