Testis-specific H1 histone (H1-7)

About Testis-specific H1 histone

Testis-specific H1 histone (H1-7) is a protein from Homo sapiens identified by UniProt accession Q75WM6, 255 residues long. MolForge cross-references it against 0 known binders and 110 disease associations.

Target properties

Protein name	Testis-specific H1 histone
UniProt accession	Q75WM6
Gene	H1-7
Organism	Homo sapiens
Length	255 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q75WM6-F1	alphafold	PREDICTED	62.89	—

Amino-acid sequence (255 residues)

MEQALTGEAQ SRWPRRGGSG AMAEAPGPSG ESRGHSATQL PAEKTVGGPS RGCSSSVLRV SQLVLQAIST HKGLTLAALK KELRNAGYEV RRKSGRHEAP RGQAKATLLR VSGSDAAGYF RVWKVPKPRR KPGRARQEEG TRAPWRTPAA PRSSRRRRQP LRKAARKARE VWRRNARAKA KANARARRTR RARPRAKEPP CARAKEEAGA TAADEGRGQA VKEDTTPRSG KDKRRSSKPR EEKQEPKKPA QRTIQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards