Nucleotide sugar transporter SLC35D2 (SLC35D2)

About Nucleotide sugar transporter SLC35D2

Nucleotide sugar transporter SLC35D2 (SLC35D2) is a protein from Homo sapiens identified by UniProt accession Q76EJ3, 337 residues long. MolForge cross-references it against 0 known binders and 46 disease associations.

Target properties

Protein name	Nucleotide sugar transporter SLC35D2
UniProt accession	Q76EJ3
Gene	SLC35D2
Organism	Homo sapiens
Length	337 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (46)

Diseases linked to this target (Open Targets).

platelet count · score 0.40
BMI-adjusted hip circumference · score 0.38
body height · score 0.34
mean platelet volume · score 0.33
self reported educational attainment · score 0.32
lean body mass · score 0.31
mean corpuscular hemoglobin concentration · score 0.30
BMI-adjusted waist circumference · score 0.29
lymphocyte count · score 0.28
mean corpuscular volume · score 0.26

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q76EJ3-F1	alphafold	PREDICTED	84.86	—

Amino-acid sequence (337 residues)

MTAGGQAEAE GAGGEPGAAR LPSRVARLLS ALFYGTCSFL IVLVNKALLT TYGFPSPIFL GIGQMAATIM ILYVSKLNKI IHFPDFDKKI PVKLFPLPLL YVGNHISGLS STSKLSLPMF TVLRKFTIPL TLLLETIILG KQYSLNIILS VFAIILGAFI AAGSDLAFNL EGYIFVFLND IFTAANGVYT KQKMDPKELG KYGVLFYNAC FMIIPTLIIS VSTGDLQQAT EFNQWKNVVF ILQFLLSCFL GFLLMYSTVL CSYYNSALTT AVVGAIKNVS VAYIGILIGG DYIFSLLNFV GLNICMAGGL RYSFLTLSSQ LKPKPVGEEN ICLDLKS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards