About Speriolin
Speriolin (SPATC1) is a protein
from Homo sapiens identified by UniProt accession
Q76KD6, 591 residues long.
MolForge cross-references it against 0 known binders and
38 disease associations.
Target properties
| Protein name | Speriolin |
|---|
| UniProt accession | Q76KD6 |
|---|
| Gene | SPATC1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 591 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (38)
Diseases linked to this target (Open Targets).
- Crohn's disease · score 0.20
- eosinophil count · score 0.17
- Alzheimer disease · score 0.17
- serum non-albumin protein measurement · score 0.16
- mean corpuscular volume · score 0.11
- fibrinogen measurement · score 0.08
- mean corpuscular hemoglobin · score 0.07
- response to statin · score 0.07
- white matter microstructure measurement · score 0.06
- low density lipoprotein cholesterol measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q76KD6-F1 | alphafold | PREDICTED | 56.09 | — |
Amino-acid sequence (591 residues)
MSLLTNYEGL RHQIERLVRE NEELKKLVRL IRENHELKSA IKTQAGGLGI SGFTSGLGEA TAGLSSRQNN GVFLPPSPAV ANERVLEEVG IMALAPLAEM LTSLQPSATP GSLMSPLTGT LSTLLSGPAP TSQSSPLTSF LTSPIAGPLT GTLASSLGLP STGTLTPSSL VAGPVAMSQS SPLIAPVMGT VAVSLSSPLL SSTATPPGVS QNLLANPMSN LVLPEAPRLR LAEPLRGGPT GPQSPACVVP TATTKVPLST EPPQSTQDPE PLSMAFAGAP LQTSTPIGAM GTPAPKTAFS FNTSDTQAQP SAAQEQVVPA SVPTSPTTSP TVTVLASAPA LAPQVATSYT PSSTTHIAQG APHPPSRMHN SPTQNLPVPH CPPHNAHSPP RTSSSPASVN DSRGPRTTEP STKSMMEVER KLAHRKTSKF PENPRESKQL AWERLVGEIA FQLDRRILSS IFPERVRLYG FTVSNIPEKI IQASLNPSDH KLDEKLCQRL TQRYVSVMNR LQSLGYNGRV HPALTEQLVN AYGILRERPE LAASEGGPYT VDFLQRVVVE TVHPGMLADA LLLLSCLSQL AHDDGKPMFI W
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