About Centrosomal protein of 68 kDa
Centrosomal protein of 68 kDa (CEP68) is a protein
from Homo sapiens identified by UniProt accession
Q76N32, 757 residues long.
MolForge cross-references it against 0 known binders and
95 disease associations.
Target properties
| Protein name | Centrosomal protein of 68 kDa |
|---|
| UniProt accession | Q76N32 |
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| Gene | CEP68 |
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| Organism | Homo sapiens |
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| Length | 757 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (95)
Diseases linked to this target (Open Targets).
- pulse pressure measurement · score 0.36
- triglyceride measurement · score 0.35
- systolic blood pressure · score 0.35
- atrial fibrillation · score 0.34
- type 2 diabetes mellitus · score 0.34
- high density lipoprotein cholesterol measurement · score 0.32
- serum alanine aminotransferase measurement · score 0.30
- sex hormone-binding globulin measurement · score 0.30
- testosterone measurement · score 0.29
- cardiovascular disease · score 0.27
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q76N32-F1 | alphafold | PREDICTED | 48.73 | — |
Amino-acid sequence (757 residues)
MALGEEKAEA EASEDTKAQS YGRGSCRERE LDIPGPMSGE QPPRLEAEGG LISPVWGAEG IPAPTCWIGT DPGGPSRAHQ PQASDANREP VAERSEPALS GLPPATMGSG DLLLSGESQV EKTKLSSSEE FPQTLSLPRT TTICSGHDAD TEDDPSLADL PQALDLSQQP HSSGLSCLSQ WKSVLSPGSA AQPSSCSISA SSTGSSLQGH QERAEPRGGS LAKVSSSLEP VVPQEPSSVV GLGPRPQWSP QPVFSGGDAS GLGRRRLSFQ AEYWACVLPD SLPPSPDRHS PLWNPNKEYE DLLDYTYPLR PGPQLPKHLD SRVPADPVLQ DSGVDLDSFS VSPASTLKSP TNVSPNCPPA EATALPFSGP REPSLKQWPS RVPQKQGGMG LASWSQLAST PRAPGSRDAR WERREPALRG AKDRLTIGKH LDMGSPQLRT RDRGWPSPRP EREKRTSQSA RRPTCTESRW KSEEEVESDD EYLALPARLT QVSSLVSYLG SISTLVTLPT GDIKGQSPLE VSDSDGPASF PSSSSQSQLP PGAALQGSGD PEGQNPCFLR SFVRAHDSAG EGSLGSSQAL GVSSGLLKTR PSLPARLDRW PFSDPDVEGQ LPRKGGEQGK ESLVQCVKTF CCQLEELICW LYNVADVTDH GTAARSNLTS LKSSLQLYRQ FKKDIDEHQS LTESVLQKGE ILLQCLLENT PVLEDVLGRI AKQSGELESH ADRLYDSILA SLDMLAGCTL IPDKKPMAAM EHPCEGV
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