Glutamate-rich protein 6 (ERICH6)

Homo sapiens — UniProt Q7L0X2

Gene: ERICH6Homo sapiensSwissProt reviewed

About Glutamate-rich protein 6

Glutamate-rich protein 6 (ERICH6) is a protein from Homo sapiens identified by UniProt accession Q7L0X2, 663 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.

Target properties

Protein nameGlutamate-rich protein 6
UniProt accessionQ7L0X2
GeneERICH6
OrganismHomo sapiens
Length663 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (11)

Diseases linked to this target (Open Targets).

  • breast carcinoma · score 0.26
  • protein measurement · score 0.24
  • lymphocyte count · score 0.14
  • response to vaccine · score 0.14
  • glycerophosphorylcholine measurement · score 0.11
  • Red cell distribution width · score 0.06
  • congenital hypothyroidism · score 0.04
  • polycystic ovary syndrome · score 0.00
  • neoplasm · score 0.00
  • cervical squamous cell carcinoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q7L0X2-F1alphafoldPREDICTED63.63—

Amino-acid sequence (663 residues)

MAHLRSPSGF GDPGKKDQKE SEEELEEEEE EEEVEEEEEE VEEEEEEVEE EEEEVVEEEL VGEEQELEAP ETFSEEYLWK VTDIGDYDDD FPDVRPRLAS IVSPSLTSTF VPSQSATSTE TPSASPPSST SSHKSFPKIF QTFRKDMSEM SIDRNIHRNL SPGIPVSVQT EESWLQDLSD KVQSRKKASK EKAEPECLAS KLREKWVINP EESKLNILYE LEFKEDFITL FEPSLRTLPS IGPPSILAYK EESSNLGINF KDEEEETSPK CEFCGSDLRA FFSNVDVSSE PKGHASCCIA FQNLIDYIYE EQIKTKPPKA ELIAIDPHAA HGSEVDRLKA KEKALQRKQE QRMARHFAII SREQTHFSED DSKRLKTISY QLSVDIPEKQ IIDDIVFDFQ LRNSNMSIIC CDSRIACGKV VRNELLEKHY KHGSKFLTSF PDGTTQIFYP SGNLAIIRVP NKVNGFTCIV QEDMPTNPAI LAVLDSSGRS SCYHPNGNVW VYINILGGQY SDQAGNRIRA WNWSNSITSS PFVSFKPVFL ALNRYIGVRI LEQDKISITF LAMGQQARIS VGTKVKLPNP EEIPILRYVS GDDLLLLASL IKIRRLFHKL EGCVNFPSSQ VWEKLKQPSY LSSLSLKLIA LCHSSGIKQD IMKTIRNIIN EEI

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Quick facts

UniProtQ7L0X2
GeneERICH6
OrganismHomo sapiens
Length663
Binders0
Diseases11
View on UniProt