About Glutamate-rich protein 6
Glutamate-rich protein 6 (ERICH6) is a protein
from Homo sapiens identified by UniProt accession
Q7L0X2, 663 residues long.
MolForge cross-references it against 0 known binders and
11 disease associations.
Target properties
| Protein name | Glutamate-rich protein 6 |
| UniProt accession | Q7L0X2 |
| Gene | ERICH6 |
| Organism | Homo sapiens |
| Length | 663 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (11)
Diseases linked to this target (Open Targets).
- breast carcinoma · score 0.26
- protein measurement · score 0.24
- lymphocyte count · score 0.14
- response to vaccine · score 0.14
- glycerophosphorylcholine measurement · score 0.11
- Red cell distribution width · score 0.06
- congenital hypothyroidism · score 0.04
- polycystic ovary syndrome · score 0.00
- neoplasm · score 0.00
- cervical squamous cell carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q7L0X2-F1 | alphafold | PREDICTED | 63.63 | — |
Amino-acid sequence (663 residues)
MAHLRSPSGF GDPGKKDQKE SEEELEEEEE EEEVEEEEEE VEEEEEEVEE EEEEVVEEEL VGEEQELEAP ETFSEEYLWK VTDIGDYDDD FPDVRPRLAS IVSPSLTSTF VPSQSATSTE TPSASPPSST SSHKSFPKIF QTFRKDMSEM SIDRNIHRNL SPGIPVSVQT EESWLQDLSD KVQSRKKASK EKAEPECLAS KLREKWVINP EESKLNILYE LEFKEDFITL FEPSLRTLPS IGPPSILAYK EESSNLGINF KDEEEETSPK CEFCGSDLRA FFSNVDVSSE PKGHASCCIA FQNLIDYIYE EQIKTKPPKA ELIAIDPHAA HGSEVDRLKA KEKALQRKQE QRMARHFAII SREQTHFSED DSKRLKTISY QLSVDIPEKQ IIDDIVFDFQ LRNSNMSIIC CDSRIACGKV VRNELLEKHY KHGSKFLTSF PDGTTQIFYP SGNLAIIRVP NKVNGFTCIV QEDMPTNPAI LAVLDSSGRS SCYHPNGNVW VYINILGGQY SDQAGNRIRA WNWSNSITSS PFVSFKPVFL ALNRYIGVRI LEQDKISITF LAMGQQARIS VGTKVKLPNP EEIPILRYVS GDDLLLLASL IKIRRLFHKL EGCVNFPSSQ VWEKLKQPSY LSSLSLKLIA LCHSSGIKQD IMKTIRNIIN EEI
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