Zinc finger protein 765 (ZNF765)

About Zinc finger protein 765

Zinc finger protein 765 (ZNF765) is a protein from Homo sapiens identified by UniProt accession Q7L2R6, 523 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.

Target properties

Protein name	Zinc finger protein 765
UniProt accession	Q7L2R6
Gene	ZNF765
Organism	Homo sapiens
Length	523 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (9)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.35
hepatocellular carcinoma · score 0.07
neoplasm · score 0.04
cancer · score 0.01
chronic kidney disease · score 0.01
metastatic malignant neoplasm · score 0.00
lymph node metastatic carcinoma · score 0.00
metastatic neoplasm · score 0.00
chromophobe renal cell carcinoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q7L2R6-F1	alphafold	PREDICTED	63.46	—

Amino-acid sequence (523 residues)

MALPQGLLTF RDVAIEFSQE EWKCLDPAQR TLYRDVMLEN YRNLVSLDIS SKCMMKEFSS TAQGNREVFH AGTSQRHESH HNGDFCFQDI DKDIHDIEFQ WQEDERNGHE ALMTKIKKLT GSTERYDQNY AGNKPVKYQL GFSFHSHLPE LHIFHTEEKI DNQVVKSIHD ASLVSTAQRI SCRPETHISN DYGNNFLNSS LFTQKQEVHM REKSFQCNDS GKAYNCSSLL RKHQLIHLGE KQYKCDICGK VFNSKRYVAR HRRCHTGEKP YKCNECGKTF SQTYYLTCHR RLHTGEKPYK CEECDKAFHF KSKLQIHRRI HTGEKPYKCN ECGKTFSQKS YLTCHRRLHT GEKPYKCNEC GKTFSRKSHF TCHHRVHTGE KPYKCNECSK TFSHKSSLTY HRRLHTEEKP YKCNECGKTF NQQLTLNICR LHSGEKPYKC EECDKAYSFK SNLEIHQKIH TEENPYKCNE CGKTFSRTSS LTYHHRLHTG QKPYKCEDCD EAFSFKSNLE RHRRIYTGEK LHV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards