About Armadillo repeat-containing X-linked protein 2
Armadillo repeat-containing X-linked protein 2 (ARMCX2) is a protein
from Homo sapiens identified by UniProt accession
Q7L311, 632 residues long.
MolForge cross-references it against 0 known binders and
17 disease associations.
Target properties
| Protein name | Armadillo repeat-containing X-linked protein 2 |
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| UniProt accession | Q7L311 |
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| Gene | ARMCX2 |
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| Organism | Homo sapiens |
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| Length | 632 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (17)
Diseases linked to this target (Open Targets).
- ovarian carcinoma · score 0.01
- neoplasm · score 0.01
- psoriasis · score 0.01
- cancer · score 0.01
- Crohn's disease · score 0.01
- gonorrhea · score 0.00
- Alzheimer disease · score 0.00
- hepatitis C virus induced hepatocellular carcinoma · score 0.00
- stomach neoplasm · score 0.00
- vulvar intraepithelial neoplasia · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q7L311-F1 | alphafold | PREDICTED | 62.59 | — |
Amino-acid sequence (632 residues)
MSRVRDAGCV AAGIVIGAGA WYCVYKYTRG RDQTKKRMAK PKNRAVAGTG ARARAGLRAG FTIDLGSGFS PPTPVRAEAE DRAQDEASAL DTVGAEAVAP AASSAEAQSG AGSQAQEADG AGVGPKAESV VGAAMASAIA PPPGVTEALG AAEAPAMAGA PKVAEAPREA ETSRAAVPPG TVVPTEAAAP TEVTEGPGVA APTKVAEAPG VASPTEAAEA PVPATPTGAA APTGAAESPG TSGSPRTAVV PGTSAAKKAT PGAHTGAIPK ATSATGAVPK GGGKGVTRSR NGGKGKGKKS KVEVDELGMG FRPGDGAAAA AAASANGGQA FLAEVPDSEE GESGWTDTES DSDSEPETQR RGRGRRPVAM QKRPFPYEID EILGVRDLRK VLALLQKSDD PFIQQVALLT LSNNANYSCN QETIRKLGGL PIIANMINKT DPHIKEKALM AMNNLSENYE NQGRLQVYMN KVMDDIMASN LNSAVQVVGL KFLTNMTITN DYQHLLVNSI ANFFRLLSQG GGKIKVEILK ILSNFAENPD MLKKLLSTQV PASFSSLYNS YVESEILINA LTLFEIIYDN LRAEVFNYRE FNKGSLFYLC TTSGVCVKKI RALANHHDLL VKVKVIKLVN KF
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