About Protein Bop
Protein Bop (RTL10) is a protein
from Homo sapiens identified by UniProt accession
Q7L3V2, 364 residues long.
MolForge cross-references it against 0 known binders and
42 disease associations.
Target properties
| Protein name | Protein Bop |
|---|
| UniProt accession | Q7L3V2 |
|---|
| Gene | RTL10 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 364 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (42)
Diseases linked to this target (Open Targets).
- intraocular pressure measurement · score 0.31
- PHF-tau measurement · score 0.20
- open-angle glaucoma · score 0.20
- glaucoma · score 0.14
- FEV/FVC ratio · score 0.08
- neurofibrillary tangles measurement · score 0.06
- status epilepticus · score 0.01
- cancer · score 0.01
- chronic lymphocytic leukemia · score 0.01
- colorectal adenoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q7L3V2-F1 | alphafold | PREDICTED | 54.08 | — |
Amino-acid sequence (364 residues)
MPRGRCRQQG PRIPIWAAAN YANAHPWQQM DKASPGVAYT PLVDPWIERP CCGDTVCVRT TMEQKSTASG TCGGKPAERG PLAGHMPSSR PHRVDFCWVP GSDPGTFDGS PWLLDRFLAQ LGDYMSFHFE HYQDNISRVC EILRRLTGRA QAWAAPYLDG DLPLPDDYEL FCQDLKEVVQ DPNSFAEYHA VVTCPLPLAS SQLPVAPQLP VVRQYLARFL EGLALDMGTA PRSLPAAMAT PAVSGSNSVS RSALFEQQLT KESTPGPKEP PVLPSSTCSS KPGPVEPASS QPEEAAPTPV PRLSESANPP AQRPDPAHPG GPKPQKTEEE VLETEGDQEV SLGTPQEVVE APETPGEPPL SPGF
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