About Lysophospholipase D GDPD3
Lysophospholipase D GDPD3 (GDPD3) is a protein
from Homo sapiens identified by UniProt accession
Q7L5L3, 318 residues long.
MolForge cross-references it against 0 known binders and
83 disease associations.
Target properties
| Protein name | Lysophospholipase D GDPD3 |
|---|
| UniProt accession | Q7L5L3 |
|---|
| Gene | GDPD3 |
|---|
| Organism | Homo sapiens |
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| Length | 318 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (83)
Diseases linked to this target (Open Targets).
- glioblastoma multiforme · score 0.23
- breast adenocarcinoma · score 0.23
- mean platelet volume · score 0.19
- head and neck squamous cell carcinoma · score 0.11
- systolic blood pressure · score 0.10
- appendicular lean mass · score 0.09
- eosinophil count · score 0.08
- FEV/FVC ratio · score 0.08
- diastolic blood pressure · score 0.08
- chronic myelogenous leukemia · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q7L5L3-F1 | alphafold | PREDICTED | 92.24 | — |
Amino-acid sequence (318 residues)
MSLLLYYALP ALGSYAMLSI FFLRRPHLLH TPRAPTFRIR LGAHRGGSGE LLENTMEAME NSMAQRSDLL ELDCQLTRDR VVVVSHDENL CRQSGLNRDV GSLDFEDLPL YKEKLEVYFS PGHFAHGSDR RMVRLEDLFQ RFPRTPMSVE IKGKNEELIR EIAGLVRRYD RNEITIWASE KSSVMKKCKA ANPEMPLSFT ISRGFWVLLS YYLGLLPFIP IPEKFFFCFL PNIINRTYFP FSCSCLNQLL AVVSKWLIMR KSLIRHLEER GVQVVFWCLN EESDFEAAFS VGATGVITDY PTALRHYLDN HGPAARTS
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