About EPM2A-interacting protein 1
EPM2A-interacting protein 1 (EPM2AIP1) is a protein
from Homo sapiens identified by UniProt accession
Q7L775, 607 residues long.
MolForge cross-references it against 0 known binders and
86 disease associations.
Target properties
| Protein name | EPM2A-interacting protein 1 |
|---|
| UniProt accession | Q7L775 |
|---|
| Gene | EPM2AIP1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 607 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (86)
Diseases linked to this target (Open Targets).
- Lynch syndrome · score 0.36
- serum gamma-glutamyl transferase measurement · score 0.35
- serum alanine aminotransferase measurement · score 0.30
- body height · score 0.28
- neurodegenerative disease · score 0.24
- C-reactive protein measurement · score 0.24
- colorectal cancer · score 0.23
- platelet component distribution width · score 0.19
- hereditary neoplastic syndrome · score 0.18
- Inherited cancer-predisposing syndrome · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q7L775-F1 | alphafold | PREDICTED | 85.29 | — |
Amino-acid sequence (607 residues)
MWMTPKRSKM EVDEALVFRP EWTQRYLVVE PPEGDGALCL VCRRLIVATR ERDVRRHYEA EHEYYERYVA DGERAALVER LRQGDLPVAS FTPEERAARA GLGLCRLLAL KGRGWGEGDF VYQCMEVLLR EVLPEHVSVL QGVDLSPDIT RQRILSIDRN LRNQLFNRAR DFKAYSLALD DQAFVAYENY LLVFIRGVGP ELEVQEDLLT IINLTHHFSV GALMSAILES LQTAGLSLQR MVGLTTTHTL RMIGENSGLV SYMREKAVSP NCWNVIHYSG FLHLELLSSY DVDVNQIINT ISEWIVLIKT RGVRRPEFQT LLTESESEHG ERVNGRCLNN WLRRGKTLKL IFSLRKEMEA FLVSVGATTV HFSDKQWLCD FGFLVDIMEH LRELSEELRV SKVFAAAAFD HICTFEVKLN LFQRHIEEKN LTDFPALREV VDELKQQNKE DEKIFDPDRY QMVICRLQKE FERHFKDLRF IKKDLELFSN PFNFKPEYAP ISVRVELTKL QANTNLWNEY RIKDLGQFYA GLSAESYPII KGVACKVASL FDSNQICEKA FSYLTRNQHT LSQPLTDEHL QALFRVATTE MEPGWDDLVR ERNESNP
Explore EPM2A-interacting protein 1 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets