About Solute carrier family 26 member 9
Solute carrier family 26 member 9 (SLC26A9) is a protein
from Homo sapiens identified by UniProt accession
Q7LBE3, 791 residues long.
MolForge cross-references it against 0 known binders and
115 disease associations.
Target properties
| Protein name | Solute carrier family 26 member 9 |
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| UniProt accession | Q7LBE3 |
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| Gene | SLC26A9 |
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| Organism | Homo sapiens |
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| Length | 791 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (115)
Diseases linked to this target (Open Targets).
- cystic fibrosis · score 0.44
- FEV/FVC ratio · score 0.37
- peak expiratory flow · score 0.30
- cystic fibrosis associated meconium ileus · score 0.26
- type 2 diabetes mellitus · score 0.24
- cutaneous melanoma · score 0.12
- monocyte count · score 0.07
- gonorrhea · score 0.06
- cortical surface area measurement · score 0.05
- hematocrit · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q7LBE3-F1 | alphafold | PREDICTED | 79.95 | — |
Amino-acid sequence (791 residues)
MSQPRPRYVV DRAAYSLTLF DDEFEKKDRT YPVGEKLRNA FRCSSAKIKA VVFGLLPVLS WLPKYKIKDY IIPDLLGGLS GGSIQVPQGM AFALLANLPA VNGLYSSFFP LLTYFFLGGV HQMVPGTFAV ISILVGNICL QLAPESKFQV FNNATNESYV DTAAMEAERL HVSATLACLT AIIQMGLGFM QFGFVAIYLS ESFIRGFMTA AGLQILISVL KYIFGLTIPS YTGPGSIVFT FIDICKNLPH TNIASLIFAL ISGAFLVLVK ELNARYMHKI RFPIPTEMIV VVVATAISGG CKMPKKYHMQ IVGEIQRGFP TPVSPVVSQW KDMIGTAFSL AIVSYVINLA MGRTLANKHG YDVDSNQEMI ALGCSNFFGS FFKIHVICCA LSVTLAVDGA GGKSQVASLC VSLVVMITML VLGIYLYPLP KSVLGALIAV NLKNSLKQLT DPYYLWRKSK LDCCIWVVSF LSSFFLSLPY GVAVGVAFSV LVVVFQTQFR NGYALAQVMD TDIYVNPKTY NRAQDIQGIK IITYCSPLYF ANSEIFRQKV IAKTGMDPQK VLLAKQKYLK KQEKRRMRPT QQRRSLFMKT KTVSLQELQQ DFENAPPTDP NNNQTPANGT SVSYITFSPD SSSPAQSEPP ASAEAPGEPS DMLASVPPFV TFHTLILDMS GVSFVDLMGI KALAKLSSTY GKIGVKVFLV NIHAQVYNDI SHGGVFEDGS LECKHVFPSI HDAVLFAQAN ARDVTPGHNF QGAPGDAELS LYDSEEDIRS YWDLEQEMFG SMFHAETLTA L
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