About Taste receptor type 2 member 42
Taste receptor type 2 member 42 (TAS2R42) is a protein
from Homo sapiens identified by UniProt accession
Q7RTR8, 314 residues long.
MolForge cross-references it against 0 known binders and
23 disease associations.
Target properties
| Protein name | Taste receptor type 2 member 42 |
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| UniProt accession | Q7RTR8 |
|---|
| Gene | TAS2R42 |
|---|
| Organism | Homo sapiens |
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| Length | 314 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Approved drugs hitting this target (1)
DrugCentral-linked approved drugs that act on this protein.
Disease associations (23)
Diseases linked to this target (Open Targets).
- ovarian cancer · score 0.18
- lung adenocarcinoma · score 0.18
- breast adenocarcinoma · score 0.16
- squamous cell lung carcinoma · score 0.13
- head and neck squamous cell carcinoma · score 0.13
- low grade glioma · score 0.10
- blood protein measurement · score 0.06
- sensory perception of bitter taste · score 0.05
- Neurofibromatosis type 6 · score 0.05
- tea consumption measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q7RTR8-F1 | alphafold | PREDICTED | 80.56 | — |
Amino-acid sequence (314 residues)
MATELDKIFL ILAIAEFIIS MLGNVFIGLV NCSEGIKNQK VFSADFILTC LAISTIGQLL VILFDSFLVG LASHLYTTYR LGKTVIMLWH MTNHLTTWLA TCLSIFYFFK IAHFPHSLFL WLRWRMNGMI VMLLILSLFL LIFDSLVLEI FIDISLNIID KSNLTLYLDE SKTLYDKLSI LKTLLSLTSF IPFSLFLTSL LFLFLSLVRH TRNLKLSSLG SRDSSTEAHR RAMKMVMSFL FLFIVHFFSL QVANWIFFML WNNKCIKFVM LALNAFPSCH SFILILGNSK LQQTAVRLLW HLRNYTKTPN PLPL
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