Pancreas transcription factor 1 subunit alpha (PTF1A)

About Pancreas transcription factor 1 subunit alpha

Pancreas transcription factor 1 subunit alpha (PTF1A) is a protein from Homo sapiens identified by UniProt accession Q7RTS3, 328 residues long. MolForge cross-references it against 0 known binders and 123 disease associations.

Target properties

Protein name	Pancreas transcription factor 1 subunit alpha
UniProt accession	Q7RTS3
Gene	PTF1A
Organism	Homo sapiens
Length	328 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q7RTS3-F1	alphafold	PREDICTED	60.37	—

Amino-acid sequence (328 residues)

MDAVLLEHFP GGLDAFPSSY FDEDDFFTDQ SSRDPLEDGD ELLADEQAEV EFLSHQLHEY CYRDGACLLL QPAPPAAPLA LAPPSSGGLG EPDDGGGGGY CCETGAPPGG FPYSPGSPPS CLAYPCAGAA VLSPGARLRG LSGAAAAAAR RRRRVRSEAE LQQLRQAANV RERRRMQSIN DAFEGLRSHI PTLPYEKRLS KVDTLRLAIG YINFLSELVQ ADLPLRGGGA GGCGGPGGGG RLGGDSPGSQ AQKVIICHRG TRSPSPSDPD YGLPPLAGHS LSWTDEKQLK EQNIIRTAKV WTPEDPRKLN SKSSFNNIEN EPPFEFVS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards