About Dymeclin
Dymeclin (DYM) is a protein
from Homo sapiens identified by UniProt accession
Q7RTS9, 669 residues long.
MolForge cross-references it against 0 known binders and
268 disease associations.
Target properties
| Protein name | Dymeclin |
|---|
| UniProt accession | Q7RTS9 |
|---|
| Gene | DYM |
|---|
| Organism | Homo sapiens |
|---|
| Length | 669 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (268)
Diseases linked to this target (Open Targets).
- Dyggve-Melchior-Clausen disease · score 0.81
- Smith-McCort dysplasia · score 0.68
- Smith-McCort dysplasia 1 · score 0.62
- genetic disorder · score 0.41
- Lethal encephalopathy due to mitochondrial and peroxisomal fission defect · score 0.37
- encephalopathy, lethal, due to defective mitochondrial peroxisomal fission 1 · score 0.37
- lean body mass · score 0.34
- waist-hip ratio · score 0.34
- BMI-adjusted waist-hip ratio · score 0.33
- body height · score 0.32
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q7RTS9-F1 | alphafold | PREDICTED | 87.06 | — |
Amino-acid sequence (669 residues)
MGSNSSRIGD LPKNEYLKKL SGTESISEND PFWNQLLSFS FPAPTSSSEL KLLEEATISV CRSLVENNPR TGNLGALIKV FLSRTKELKL SAECQNHIFI WQTHNALFII CCLLKVFICQ MSEEELQLHF TYEEKSPGNY SSDSEDLLEE LLCCLMQLIT DIPLLDITYE ISVEAISTMV VFLSCQLFHK EVLRQSISHK YLMRGPCLPY TSKLVKTLLY NFIRQEKPPP PGAHVFPQQS DGGGLLYGLA SGVATGLWTV FTLGGVGSKA AASPELSSPL ANQSLLLLLV LANLTDASDA PNPYRQAIMS FKNTQDSSPF PSSIPHAFQI NFNSLYTALC EQQTSDQATL LLYTLLHQNS NIRTYMLART DMENLVLPIL EILYHVEERN SHHVYMALII LLILTEDDGF NRSIHEVILK NITWYSERVL TEISLGSLLI LVVIRTIQYN MTRTRDKYLH TNCLAALANM SAQFRSLHQY AAQRIISLFS LLSKKHNKVL EQATQSLRGS LSSNDVPLPD YAQDLNVIEE VIRMMLEIIN SCLTNSLHHN PNLVYALLYK RDLFEQFRTH PSFQDIMQNI DLVISFFSSR LLQAGAELSV ERVLEIIKQG VVALPKDRLK KFPELKFKYV EEEQPEEFFI PYVWSLVYNS AVGLYWNPQD IQLFTMDSD
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