About Transcription factor 23
Transcription factor 23 (TCF23) is a protein
from Homo sapiens identified by UniProt accession
Q7RTU1, 214 residues long.
MolForge cross-references it against 0 known binders and
9 disease associations.
Target properties
| Protein name | Transcription factor 23 |
|---|
| UniProt accession | Q7RTU1 |
|---|
| Gene | TCF23 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 214 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (9)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.21
- cardiovascular disease · score 0.13
- urate measurement · score 0.12
- central nervous system cancer · score 0.03
- endometrial carcinoma · score 0.03
- COVID-19 · score 0.01
- Tetralogy of Fallot · score 0.01
- gastric carcinoma · score 0.00
- Colon Sessile Serrated Adenoma/Polyp · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q7RTU1-F1 | alphafold | PREDICTED | 62.52 | — |
Amino-acid sequence (214 residues)
MSQRKARGPP AMPGVGHSQT QAKARLLPGA DRKRSRLSRT RQDPWEERSW SNQRWSRATP GPRGTRAGGL ALGRSEASPE NAARERSRVR TLRQAFLALQ AALPAVPPDT KLSKLDVLVL AASYIAHLTR TLGHELPGPA WPPFLRGLRY LHPLKKWPMR SRLYAGGLGY SDLDSTTAST PSQRTRDAEV GSQVPGEADA LLSTTPLSPA LGDK
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