About Glutathione S-transferase A5
Glutathione S-transferase A5 (GSTA5) is a protein
from Homo sapiens identified by UniProt accession
Q7RTV2, 222 residues long.
MolForge cross-references it against 0 known binders and
39 disease associations.
Target properties
| Protein name | Glutathione S-transferase A5 |
|---|
| UniProt accession | Q7RTV2 |
|---|
| Gene | GSTA5 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 222 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (39)
Diseases linked to this target (Open Targets).
- protein measurement · score 0.34
- platelet count · score 0.31
- vitamin C measurement · score 0.26
- high density lipoprotein cholesterol measurement · score 0.22
- erythrocyte count · score 0.22
- testosterone measurement · score 0.21
- hemoglobin measurement · score 0.20
- Red cell distribution width · score 0.18
- glioblastoma multiforme · score 0.16
- hematocrit · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q7RTV2-F1 | alphafold | PREDICTED | 97.27 | — |
Amino-acid sequence (222 residues)
MAEKPKLHYS NARGSMESIR WLLAAAGVEL EEKFLESAED LDKLRNDGSL LFQQVPMVEI DGMKLVQTRA ILNYIASKYN LYGKDMKERA LIDMYTEGIV DLTEMILLLL ICQPEERDAK TALVKEKIKN RYFPAFEKVL KSHRQDYLVG NKLSWADIHL VELFYYVEEL DSSLISSFPL LKALKTRISN LPTVKKFLQP GSQRKPPMDE KSLEEARKIF RF
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