Histone H2B type W-T (H2BW1)

About Histone H2B type W-T

Histone H2B type W-T (H2BW1) is a protein from Homo sapiens identified by UniProt accession Q7Z2G1, 153 residues long. MolForge cross-references it against 0 known binders and 3 disease associations.

Target properties

Protein name	Histone H2B type W-T
UniProt accession	Q7Z2G1
Gene	H2BW1
Organism	Homo sapiens
Length	153 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (3)

Diseases linked to this target (Open Targets).

pancreatic adenocarcinoma · score 0.04
non-small cell lung carcinoma · score 0.03
male infertility · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q7Z2G1-F1	alphafold	PREDICTED	76.52	—

Amino-acid sequence (153 residues)

MATASAMAGP SSETTSEEQL ITQEPKEANS TTSQKQSKQR KRGRHGPRRC HSNCRGDSFA TYFRRVLKQV HQGLSLSREA VSVMDSLVHD ILDRIATEAG HLARSTKRQT ITAWETRMAV RLLLPGQMGK LAESEGTKAV LRTSLYAIQQ QRK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards