About Large ribosomal subunit protein bL21m
Large ribosomal subunit protein bL21m (MRPL21) is a protein
from Homo sapiens identified by UniProt accession
Q7Z2W9, 205 residues long.
MolForge cross-references it against 0 known binders and
27 disease associations.
Target properties
| Protein name | Large ribosomal subunit protein bL21m |
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| UniProt accession | Q7Z2W9 |
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| Gene | MRPL21 |
|---|
| Organism | Homo sapiens |
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| Length | 205 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (27)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- lysosomal storage disease · score 0.22
- high density lipoprotein cholesterol measurement · score 0.15
- apolipoprotein A 1 measurement · score 0.11
- cataract · score 0.11
- triglyceride measurement · score 0.07
- forced expiratory volume · score 0.07
- body mass index · score 0.07
- protein measurement · score 0.06
- hepatocellular carcinoma · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q7Z2W9-F1 | alphafold | PREDICTED | 84.83 | — |
Amino-acid sequence (205 residues)
MAASSLTVTL GRLASACSHS ILRPSGPGAA SLWSASRRFN SQSTSYLPGY VPKTSLSSPP WPEVVLPDPV EETRHHAEVV KKVNEMIVTG QYGRLFAVVH FASRQWKVTS EDLILIGNEL DLACGERIRL EKVLLVGADN FTLLGKPLLG KDLVRVEATV IEKTESWPRI IMRFRKRKNF KKKRIVTTPQ TVLRINSIEI APCLL
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