About Treslin
Treslin (TICRR) is a protein
from Homo sapiens identified by UniProt accession
Q7Z2Z1, 1910 residues long.
MolForge cross-references it against 0 known binders and
70 disease associations.
Target properties
| Protein name | Treslin |
|---|
| UniProt accession | Q7Z2Z1 |
|---|
| Gene | TICRR |
|---|
| Organism | Homo sapiens |
|---|
| Length | 1910 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (70)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.38
- mean corpuscular hemoglobin · score 0.37
- mean corpuscular hemoglobin concentration · score 0.37
- body height · score 0.31
- Diuretic use measurement · score 0.30
- Agents acting on the renin-angiotensin system use measurement · score 0.29
- brain measurement · score 0.28
- chronic obstructive pulmonary disease · score 0.20
- oxygen saturation measurement · score 0.20
- neurodegenerative disease · score 0.16
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q7Z2Z1-F1 | alphafold | PREDICTED | 47.67 | — |
Amino-acid sequence (1910 residues)
MACCHKVMLL LDTAGGAARH SRVRRAALRL LTYLSCRFGL ARVHWAFKFF DSQGARSRPS RVSDFRELGS RSWEDFEEEL EARLEDRAHL PGPAPRATHT HGALMETLLD YQWDRPEITS PTKPILRSSG RRLLDVESEA KEAEAALGGL VNAVFLLAPC PHSQRELLQF VSGCEAQAQR LPPTPKQVME KLLPKRVREV MVARKITFYW VDTTEWSKLW ESPDHLGYWT VCELLHHGGG TVLPSESFSW DFAQAGEMLL RSGIKLSSEP HLSPWISMLP TDATLNRLLY NSPEYEASFP RMEGMLFLPV EAGKEIQETW TVTLEPLAMH QRHFQKPVRI FLKGSVAQWS LPTSSTLGTD SWMLGSPEES TATQRLLFQQ LVSRLTAEEL HLVADVDPGE GRPPITGVIS PLSASAMILT VCRTKEAEFQ RHVLQTAVAD SPRDTASLFS DVVDSILNQT HDSLADTASA ASPVPEWAQQ ELGHTTPWSP AVVEKWFPFC NISGASSDLM ESFGLLQAAS ANKEESSKTE GELIHCLAEL YQRKSREEST IAHQEDSKKK RGVPRTPVRQ KMNTMCRSLK MLNVARLNVK AQKLHPDGSP DVAGEKGIQK IPSGRTVDKL EDRGRTLRSS KPKDFKTEEE LLSYIRENYQ KTVATGEIML YACARNMIST VKMFLKSKGT KELEVNCLNQ VKSSLLKTSK SLRQNLGKKL DKEDKVRECQ LQVFLRLEMC LQCPSINEST DDMEQVVEEV TDLLRMVCLT EDSAYLAEFL EEILRLYIDS IPKTLGNLYN SLGFVIPQKL AGVLPTDFFS DDSMTQENKS PLLSVPFLSS ARRSVSGSPE SDELQELRTR SAKKRRKNAL IRHKSIAEVS QNLRQIEIPK VSKRATKKEN SHPAPQQPSQ PVKDTVQEVT KVRRNLFNQE LLSPSKRSLK RGLPRSHSVS AVDGLEDKLD NFKKNKGYHK LLTKSVAETP VHKQISKRLL HRQIKGRSSD PGPDIGVVEE SPEKGDEISL RRSPRIKQLS FSRTHSASFY SVSQPKSRSV QRVHSFQQDK SDQRENSPVQ SIRSPKSLLF GAMSEMISPS EKGSARMKKR SRNTLDSEVP AAYQTPKKSH QKSLSFSKTT PRRISHTPQT PLYTPERLQK SPAKMTPTKQ AAFKESLKDS SSPGHDSPLD SKITPQKRHT QAGEGTSLET KTPRTPKRQG TQPPGFLPNC TWPHSVNSSP ESPSCPAPPT SSTAQPRREC LTPIRDPLRT PPRAAAFMGT PQNQTHQQPH VLRAARAEEP AQKLKDKAIK TPKRPGNSTV TSSPPVTPKK LFTSPLCDVS KKSPFRKSKI ECPSPGELDQ KEPQMSPSVA ASLSCPVPST PPELSQRATL DTVPPPPPSK VGKRCRKTSD PRRSIVECQP DASATPGVGT ADSPAAPTDS RDDQKGLSLS PQSPPERRGY PGPGLRSDWH ASSPLLITSD TEHVTLLSEA EHHGIGDLKS NVLSVEEGEG LRTADAEKSS LSHPGIPPSP PSCGPGSPLM PSRDVHCTTD GRQCQASAQL DNLPASAWHS TDSASPQTYE VELEMQASGL PKLRIKKIDP SSSLEAEPLS KEESSLGEES FLPALSMPRA SRSLSKPEPT YVSPPCPRLS HSTPGKSRGQ TYICQACTPT HGPSSTPSPF QTDGVPWTPS PKHSGKTTPD IIKDWPRRKR AVGCGAGSSS GRGEVGADLP GSLSLLESEG KDHGLELSIH RTPILEDFEL EGVCQLPDQS PPRNSMPKAE EASSWGQFGL SSRKRVLLAK EEADRGAKRI CDLREDSEVS KSKEGSPSWS AWQLPSTGDE EVFVSGSTPP PSCAVRSCLS ASALQALTQS PLLFQGKTPS SQSKDPRDED VDVLPSTVED SPFSRAFSRR RPISRTYTRK KLMGTWLEDL
Explore Treslin with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets