About FMR1-interacting protein NUFIP2
FMR1-interacting protein NUFIP2 (NUFIP2) is a protein
from Homo sapiens identified by UniProt accession
Q7Z417, 695 residues long.
MolForge cross-references it against 0 known binders and
69 disease associations.
Target properties
| Protein name | FMR1-interacting protein NUFIP2 |
|---|
| UniProt accession | Q7Z417 |
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| Gene | NUFIP2 |
|---|
| Organism | Homo sapiens |
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| Length | 695 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (69)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- electrocardiography · score 0.29
- glucose measurement · score 0.25
- mean platelet volume · score 0.25
- mathematical ability · score 0.23
- leukocyte count · score 0.23
- Red cell distribution width · score 0.23
- platelet count · score 0.23
- myeloid white cell count · score 0.23
- monocyte count · score 0.22
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q7Z417-F1 | alphafold | PREDICTED | 47.66 | — |
Amino-acid sequence (695 residues)
MEEKPGQPQP QHHHSHHHPH HHPQQQQQQP HHHHHYYFYN HSHNHHHHHH HQQPHQYLQH GAEGSPKAQP KPLKHEQKHT LQQHQETPKK KTGYGELNGN AGEREISLKN LSSDEATNPI SRVLNGNQQV VDTSLKQTVK ANTFGKAGIK TKNFIQKNSM DKKNGKSYEN KSGENQSVDK SDTIPIPNGV VTNNSGYITN GYMGKGADND GSGSESGYTT PKKRKARRNS AKGCENLNIV QDKIMQQETS VPTLKQGLET FKPDYSEQKG NRVDGSKPIW KYETGPGGTS RGKPAVGDML RKSSDSKPGV SSKKFDDRPK GKHASAVASK EDSWTLFKPP PVFPVDNSSA KIVPKISYAS KVKENLNKTI QNSSVSPTSS SSSSSSTGET QTQSSSRLSQ VPMSALKSVT SANFSNGPVL AGTDGNVYPP GGQPLLTTAA NTLTPISSGT DSVLQDMSLT SAAVEQIKTS LFIYPSNMQT MLLSTAQVDL PSQTDQQNLG DIFQNQWGLS FINEPSAGPE TVTGKSSEHK VMEVTFQGEY PATLVSQGAE IIPSGTEHPV FPKAYELEKR TSPQVLGSIL KSGTTSESGA LSLEPSHIGD LQKADTSSQG ALVFLSKDYE IESQNPLASP TNTLLGSAKE QRYQRGLERN DSWGSFDLRA AIVYHTKEME SIWNLQKQDP KRIITYNEAM DSPDQ
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