About Zinc finger protein 804A
Zinc finger protein 804A (ZNF804A) is a protein
from Homo sapiens identified by UniProt accession
Q7Z570, 1209 residues long.
MolForge cross-references it against 0 known binders and
136 disease associations.
Target properties
| Protein name | Zinc finger protein 804A |
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| UniProt accession | Q7Z570 |
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| Gene | ZNF804A |
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| Organism | Homo sapiens |
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| Length | 1209 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (136)
Diseases linked to this target (Open Targets).
- schizophrenia · score 0.52
- bipolar disorder · score 0.45
- neuroticism measurement · score 0.44
- unipolar depression · score 0.42
- self reported educational attainment · score 0.41
- attention deficit hyperactivity disorder · score 0.41
- wellbeing measurement · score 0.40
- autism spectrum disorder · score 0.40
- breakfast skipping measurement · score 0.37
- age at first sexual intercourse measurement · score 0.35
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q7Z570-F1 | alphafold | PREDICTED | 45.14 | — |
Amino-acid sequence (1209 residues)
MECYYIVISS THLSNGHFRN IKGVFRGPLS KNGNKTLDYA EKENTIAKAL EDLKANFYCE LCDKQYYKHQ EFDNHINSYD HAHKQRLKEL KQREFARNVA SKSRKDERKQ EKALQRLHKL AELRKETVCA PGSGPMFKST TVTVRENCNE ISQRVVVDSV NNQQDFKYTL IHSEENTKDA TTVAEDPESA NNYTAKNNQV GDQAQGIHRH KIGFSFAFPK KASVKLESSA AAFSEYSDDA SVGKGFSRKS RFVPSACHLQ QSSPTDVLLS SEEKTNSFHP PEAMCRDKET VQTQEIKEVS SEKDALLLPS FCKFQLQLSS DADNCQNSVP LADQIPLESV VINEDIPVSG NSFELLGNKS TVLDMSNDCI SVQATTEENV KHNEASTTEV ENKNGPETLA PSNTEEVNIT IHKKTNFCKR QCEPFVPVLN KHRSTVLQWP SEMLVYTTTK PSISYSCNPL CFDFKSTKVN NNLDKNKPDL KDLCSQQKQE DICMGPLSDY KDVSTEGLTD YEIGSSKNKC SQVTPLLADD ILSSSCDSGK NENTGQRYKN ISCKIRETEK YNFTKSQIKQ DTLDEKYNKI RLKETHEYWF HKSRRKKKRK KLCQHHHMEK TKESETRCKM EAENSYTENA GKYLLEPISE KQYLAAEQLL DSHQLLDKRP KSESISLSDN EEMCKTWNTE YNTYDTISSK NHCKKNTILL NGQSNATMIH SGKHNLTYSR TYCCWKTKMS SCSQDHRSLV LQNDMKHMSQ NQAVKRGYNS VMNESERFYR KRRQHSHSYS SDESLNRQNH LPEEFLRPPS TSVAPCKPKK KRRRKRGRFH PGFETLELKE NTDYPVKDNS SLNPLDRLIS EDKKEKMKPQ EVAKIERNSE QTNQLRNKLS FHPNNLLPSE TNGETEHLEM ETTSGELSDV SNDPTTSVCV ASAPTKEAID NTLLEHKERS ENINLNEKQI PFQVPNIERN FRQSQPKSYL CHYELAEALP QGKMNETPTE WLRYNSGILN TQPPLPFKEA HVSGHTFVTA EQILAPLALP EQALLIPLEN HDKFKNVPCE VYQHILQPNM LANKVKFTFP PAALPPPSTP LQPLPLQQSL CSTSVTTIHH TVLQQHAAAA AAAAAAAAAG TFKVLQPHQQ FLSQIPALTR TSLPQLSVGP VGPRLCPGNQ PTFVAPPQMP IIPASVLHPS HLAFPSLPHA LFPSLLSPHP TVIPLQPLF
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