About Coiled-coil domain-containing protein R3HCC1L
Coiled-coil domain-containing protein R3HCC1L (R3HCC1L) is a protein
from Homo sapiens identified by UniProt accession
Q7Z5L2, 792 residues long.
MolForge cross-references it against 0 known binders and
41 disease associations.
Target properties
| Protein name | Coiled-coil domain-containing protein R3HCC1L |
|---|
| UniProt accession | Q7Z5L2 |
|---|
| Gene | R3HCC1L |
|---|
| Organism | Homo sapiens |
|---|
| Length | 792 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (41)
Diseases linked to this target (Open Targets).
- body mass index · score 0.28
- body height · score 0.28
- PHF-tau measurement · score 0.27
- carpal tunnel syndrome · score 0.27
- neurodegenerative disease · score 0.24
- pulse pressure measurement · score 0.09
- metabolite measurement · score 0.07
- Blackfan-Diamond anemia · score 0.07
- hereditary persistence of fetal hemoglobin-sickle cell disease syndrome · score 0.06
- hemoglobin D disease · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q7Z5L2-F1 | alphafold | PREDICTED | 50.77 | — |
Amino-acid sequence (792 residues)
MQQESERCRV RARRPDMALY VPKARRGAVL LKTGDEEESC GSPNSVVKEK QKESSLSQKE VFKDKPEARR LNINPDRKEH NCREEKKSST KLRMDTCLQK TNRVCSKRGT TESKEVLSQG QQQGAPNAGV ITNAPLQRHF KPKKVECLEV ETTDVTGHER ILLSQACLEI SEAQVPSKPF QNVEFCDFSR HEPDGEAFED KDLEGRIETD TKVLEILYEF PRVFSSVMKP ENMIVPIKLS SDSEIVQQSM QTSDGILNPS SGGITTTSVP GSPDGVFDQT CVDFEVESVG GIANSTGFIL DQKDTDSIPA TMGHISLSES TNDTVSPVMI RECEKNDSTA DELHVKHEPP DTAVLAHETH RDSGFKNVGD ITNKACMMDT TGMSCSDHVT VDSPYVVAVR IADETSINTR SFSKFVGMSA DATPLHVARS GNDTEDFSNP SACSDIYGES ISSHFTESTG KLIESLSDCA SSLPIKKIAG SNYNTFLDSE LSMLNGTKVL SDSAVGIDLG STGDTTEALH ELRTAEEFKT EEQDDSGSIE FGVSFPDRES SSMETSIEPK ATETSHTEGI TAIEESWESM FNDDGDCLDP RLLQEGILMH IKPENHCSKL SGNTKSRESI QEPRSDYYNH EVPDIDLSDC EFPHVIEIYD FPQEFHTEDL LRVFCSYQKK GFDIKWVDDT HALGVFSSPI TARDALGIKH TMVKIRPLSQ ATRAAKAKAR AYAEFLQPAK ERPETSAALA RRLVISALGV RSKQSKTERE AELKKLQEAR ERKRLEAKQR EDIWEGRDQS TV
Explore Coiled-coil domain-containing protein R3HCC1L with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets