About Neuroepithelial cell-transforming gene 1 protein
Neuroepithelial cell-transforming gene 1 protein (NET1) is a protein
from Homo sapiens identified by UniProt accession
Q7Z628, 596 residues long.
MolForge cross-references it against 0 known binders and
41 disease associations.
Target properties
| Protein name | Neuroepithelial cell-transforming gene 1 protein |
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| UniProt accession | Q7Z628 |
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| Gene | NET1 |
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| Organism | Homo sapiens |
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| Length | 596 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (41)
Diseases linked to this target (Open Targets).
- sitting height measurement · score 0.29
- myeloid white cell count · score 0.19
- breast adenocarcinoma · score 0.18
- triglyceride measurement · score 0.14
- sleep duration · score 0.13
- ependymoma · score 0.11
- acute lymphoblastic leukemia · score 0.07
- IGF-1 measurement · score 0.07
- sex hormone-binding globulin measurement · score 0.06
- alkaline phosphatase measurement · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q7Z628-F1 | alphafold | PREDICTED | 69.62 | — |
Amino-acid sequence (596 residues)
MEPELAAQKQ PRPRRRSRRA SGLSTEGATG PSADTSGSEL DGRCSLRRGS SFTFLTPGPN WDFTLKRKRR EKDDDVVSLS SLDLKEPSNK RVRPLARVTS LANLISPVRN GAVRRFGQTI QSFTLRGDHR SPASAQKFSS RSTVPTPAKR RSSALWSEML DITMKESLTT REIRRQEAIY EMSRGEQDLI EDLKLARKAY HDPMLKLSIM SEEELTHIFG DLDSYIPLHE DLLTRIGEAT KPDGTVEQIG HILVSWLPRL NAYRGYCSNQ LAAKALLDQK KQDPRVQDFL QRCLESPFSR KLDLWSFLDI PRSRLVKYPL LLKEILKHTP KEHPDVQLLE DAILIIQGVL SDINLKKGES ECQYYIDKLE YLDEKQRDPR IEASKVLLCH GELRSKSGHK LYIFLFQDIL VLTRPVTRNE RHSYQVYRQP IPVQELVLED LQDGDVRMGG SFRGAFSNSE KAKNIFRIRF HDPSPAQSHT LQANDVFHKQ QWFNCIRAAI APFQSAGSPP ELQGLPELHE ECEGNHPSAR KLTAQRRAST VSSVTQVEVD ENAYRCGSGM QMAEDSKSLK THQTQPGIRR ARDKALSGGK RKETLV
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