Sprouty-related, EVH1 domain-containing protein 2 (SPRED2)

About Sprouty-related, EVH1 domain-containing protein 2

Sprouty-related, EVH1 domain-containing protein 2 (SPRED2) is a protein from Homo sapiens identified by UniProt accession Q7Z698, 418 residues long. MolForge cross-references it against 0 known binders and 208 disease associations.

Target properties

Protein name	Sprouty-related, EVH1 domain-containing protein 2
UniProt accession	Q7Z698
Gene	SPRED2
Organism	Homo sapiens
Length	418 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q7Z698-F1	alphafold	PREDICTED	68.69	—

Amino-acid sequence (418 residues)

MTEETHPDDD SYIVRVKAVV MTRDDSSGGW FPQEGGGISR VGVCKVMHPE GNGRSGFLIH GERQKDKLVV LECYVRKDLV YTKANPTFHH WKVDNRKFGL TFQSPADARA FDRGVRKAIE DLIEGSTTSS STIHNEAELG DDDVFTTATD SSSNSSQKRE QPTRTISSPT SCEHRRIYTL GHLHDSYPTD HYHLDQPMPR PYRQVSFPDD DEEIVRINPR EKIWMTGYED YRHAPVRGKY PDPSEDADSS YVRFAKGEVP KHDYNYPYVD SSDFGLGEDP KGRGGSVIKT QPSRGKSRRR KEDGERSRCV YCRDMFNHEE NRRGHCQDAP DSVRTCIRRV SCMWCADSML YHCMSDPEGD YTDPCSCDTS DEKFCLRWMA LIALSFLAPC MCCYLPLRAC YHCGVMCRCC GGKHKAAA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards