About RNA-binding Raly-like protein
RNA-binding Raly-like protein (RALYL) is a protein
from Homo sapiens identified by UniProt accession
Q86SE5, 291 residues long.
MolForge cross-references it against 0 known binders and
66 disease associations.
Target properties
| Protein name | RNA-binding Raly-like protein |
|---|
| UniProt accession | Q86SE5 |
|---|
| Gene | RALYL |
|---|
| Organism | Homo sapiens |
|---|
| Length | 291 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (66)
Diseases linked to this target (Open Targets).
- body mass index · score 0.42
- metabolite measurement · score 0.37
- neurofibrillary tangles measurement · score 0.32
- intelligence · score 0.31
- neurodegenerative disease · score 0.29
- body weight · score 0.26
- lean body mass · score 0.23
- base metabolic rate measurement · score 0.22
- PHF-tau measurement · score 0.17
- body height · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86SE5-F1 | alphafold | PREDICTED | 70.87 | — |
Amino-acid sequence (291 residues)
MTGKTQTSNV TNKNDPKSIN SRVFIGNLNT AIVKKVDIEA IFSKYGKIVG CSVHKGYAFV QYMSERHARA AVAGENARVI AGQPLDINMA GEPKPYRPKP GNKRPLSALY RLESKEPFLS VGGYVFDYDY YRDDFYNRLF DYHGRVPPPP RAVIPLKRPR VAVTTTRRGK GVFSMKGGSR STASGSTGSK LKSDELQTIK KELTQIKTKI DSLLGRLEKI EKQQKAEAEA QKKQLEESLV LIQEECVSEI ADHSTEEPAE GGPDADGEEM TDGIEEDFDE DGGHELFLQI K
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