About Polycomb group RING finger protein 5
Polycomb group RING finger protein 5 (PCGF5) is a protein
from Homo sapiens identified by UniProt accession
Q86SE9, 256 residues long.
MolForge cross-references it against 0 known binders and
35 disease associations.
Target properties
| Protein name | Polycomb group RING finger protein 5 |
|---|
| UniProt accession | Q86SE9 |
|---|
| Gene | PCGF5 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 256 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (35)
Diseases linked to this target (Open Targets).
- body height · score 0.41
- hemoglobin measurement · score 0.39
- hematocrit · score 0.34
- vital capacity · score 0.34
- body mass index · score 0.33
- BMI-adjusted waist circumference · score 0.33
- forced expiratory volume · score 0.30
- sitting height measurement · score 0.27
- appendicular lean mass · score 0.27
- BMI-adjusted hip circumference · score 0.27
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86SE9-F1 | alphafold | PREDICTED | 80.46 | — |
Amino-acid sequence (256 residues)
MATQRKHLVK DFNPYITCYI CKGYLIKPTT VTECLHTFCK TCIVQHFEDS NDCPRCGNQV HETNPLEMLR LDNTLEEIIF KLVPGLREQE LERESEFWKK NKPQENGQDD TSKADKPKVD EEGDENEDDK DYHRSDPQIA ICLDCLRNNG QSGDNVVKGL MKKFIRCSTR VTVGTIKKFL SLKLKLPSSY ELDVLCNGEI MGKDHTMEFI YMTRWRLRGE NFRCLNCSAS QVCSQDGPLY QSYPMVLQYR PRIDFG
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