About N-acetylgalactosaminyltransferase 7
N-acetylgalactosaminyltransferase 7 (GALNT7) is a protein
from Homo sapiens identified by UniProt accession
Q86SF2, 657 residues long.
MolForge cross-references it against 0 known binders and
38 disease associations.
Target properties
| Protein name | N-acetylgalactosaminyltransferase 7 |
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| UniProt accession | Q86SF2 |
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| Gene | GALNT7 |
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| Organism | Homo sapiens |
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| Length | 657 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (38)
Diseases linked to this target (Open Targets).
- alcohol consumption measurement · score 0.39
- self reported educational attainment · score 0.34
- neuritic plaque measurement · score 0.32
- alcohol use disorder measurement · score 0.31
- glioblastoma multiforme · score 0.13
- papillary thyroid carcinoma · score 0.08
- body mass index · score 0.05
- cancer · score 0.04
- bone density · score 0.04
- gut microbiome measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86SF2-F1 | alphafold | PREDICTED | 87.67 | — |
Amino-acid sequence (657 residues)
MRLKIGFILR SLLVVGSFLG LVVLWSSLTP RPDDPSPLSR MREDRDVNDP MPNRGGNGLA PGEDRFKPVV PWPHVEGVEV DLESIRRINK AKNEQEHHAG GDSQKDIMQR QYLTFKPQTF TYHDPVLRPG ILGNFEPKEP EPPGVVGGPG EKAKPLVLGP EFKQAIQASI KEFGFNMVAS DMISLDRSVN DLRQEECKYW HYDENLLTSS VVIVFHNEGW STLMRTVHSV IKRTPRKYLA EIVLIDDFSN KEHLKEKLDE YIKLWNGLVK VFRNERREGL IQARSIGAQK AKLGQVLIYL DAHCEVAVNW YAPLVAPISK DRTICTVPLI DVINGNTYEI IPQGGGDEDG YARGAWDWSM LWKRVPLTPQ EKRLRKTKTE PYRSPAMAGG LFAIEREFFF ELGLYDPGLQ IWGGENFEIS YKIWQCGGKL LFVPCSRVGH IYRLEGWQGN PPPIYVGSSP TLKNYVRVVE VWWDEYKDYF YASRPESQAL PYGDISELKK FREDHNCKSF KWFMEEIAYD ITSHYPLPPK NVDWGEIRGF ETAYCIDSMG KTNGGFVELG PCHRMGGNQL FRINEANQLM QYDQCLTKGA DGSKVMITHC NLNEFKEWQY FKNLHRFTHI PSGKCLDRSE VLHQVFISNC DSSKTTQKWE MNNIHSV
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