Mas-related G-protein coupled receptor member G (MRGPRG)

About Mas-related G-protein coupled receptor member G

Mas-related G-protein coupled receptor member G (MRGPRG) is a protein from Homo sapiens identified by UniProt accession Q86SM5, 289 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.

Target properties

Protein name	Mas-related G-protein coupled receptor member G
UniProt accession	Q86SM5
Gene	MRGPRG
Organism	Homo sapiens
Length	289 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q86SM5-F1	alphafold	PREDICTED	86.08	—

Amino-acid sequence (289 residues)

MFGLFGLWRT FDSVVFYLTL IVGLGGPVGN GLVLWNLGFR IKKGPFSIYL LHLAAADFLF LSCRVGFSVA QAALGAQDTL YFVLTFLWFA VGLWLLAAFS VERCLSDLFP ACYQGCRPRH ASAVLCALVW TPTLPAVPLP ANACGLLRNS ACPLVCPRYH VASVTWFLVL ARVAWTAGVV LFVWVTCCST RPRPRLYGIV LGALLLLFFC GLPSVFYWSL QPLLNFLLPV FSPLATLLAC VNSSSKPLIY SGLGRQPGKR EPLRSVLRRA LGEGAELGAR GQSLPMGLL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards