About Serologically defined colon cancer antigen 8
Serologically defined colon cancer antigen 8 (SDCCAG8) is a protein
from Homo sapiens identified by UniProt accession
Q86SQ7, 713 residues long.
MolForge cross-references it against 0 known binders and
217 disease associations.
Target properties
| Protein name | Serologically defined colon cancer antigen 8 |
|---|
| UniProt accession | Q86SQ7 |
|---|
| Gene | SDCCAG8 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 713 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (217)
Diseases linked to this target (Open Targets).
- Senior-Loken syndrome 7 · score 0.78
- Bardet-Biedl syndrome 16 · score 0.75
- Senior-Loken syndrome · score 0.69
- Bardet-Biedl syndrome · score 0.69
- genetic disorder · score 0.41
- Obesity · score 0.37
- Intellectual disability · score 0.37
- obesity · score 0.37
- schizophrenia · score 0.36
- diastolic blood pressure · score 0.36
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86SQ7-F1 | alphafold | PREDICTED | 77.95 | — |
Amino-acid sequence (713 residues)
MAKSPENSTL EEILGQYQRS LREHASRSIH QLTCALKEGD VTIGEDAPNL SFSTSVGNED ARTAWPELQQ SHAVNQLKDL LRQQADKESE VSPSRRRKMS PLRSLEHEET NMPTMHDLVH TINDQSQYIH HLEAEVKFCK EELSGMKNKI QVVVLENEGL QQQLKSQRQE ETLREQTLLD ASGNMHNSWI TTGEDSGVGE TSKRPFSHDN ADFGKAASAG EQLELEKLKL TYEEKCEIEE SQLKFLRNDL AEYQRTCEDL KEQLKHKEFL LAANTCNRVG GLCLKCAQHE AVLSQTHTNV HMQTIERLVK ERDDLMSALV SVRSSLADTQ QREASAYEQV KQVLQISEEA NFEKTKALIQ CDQLRKELER QAERLEKELA SQQEKRAIEK DMMKKEITKE REYMGSKMLI LSQNIAQLEA QVEKVTKEKI SAINQLEEIQ SQLASREMDV TKVCGEMRYQ LNKTNMEKDE AEKEHREFRA KTNRDLEIKD QEIEKLRIEL DESKQHLEQE QQKAALAREE CLRLTELLGE SEHQLHLTRQ EKDSIQQSFS KEAKAQALQA QQREQELTQK IQQMEAQHDK TENEQYLLLT SQNTFLTKLK EECCTLAKKL EQISQKTRSE IAQLSQEKRY TYDKLGKLQR RNEELEEQCV QHGRVHETMK QRLRQLDKHS QATAQQLVQL LSKQNQLLLE RQSLSEEVDR LRTQLPSMPQ SDC
Explore Serologically defined colon cancer antigen 8 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets