About Tubulin epsilon and delta complex protein 1
Tubulin epsilon and delta complex protein 1 (TEDC1) is a protein
from Homo sapiens identified by UniProt accession
Q86SX3, 495 residues long.
MolForge cross-references it against 0 known binders and
41 disease associations.
Target properties
| Protein name | Tubulin epsilon and delta complex protein 1 |
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| UniProt accession | Q86SX3 |
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| Gene | TEDC1 |
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| Organism | Homo sapiens |
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| Length | 495 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (41)
Diseases linked to this target (Open Targets).
- total blood protein measurement · score 0.24
- serum albumin measurement · score 0.22
- blood protein measurement · score 0.19
- serum non-albumin protein measurement · score 0.18
- calcium measurement · score 0.17
- immunoglobulin isotype switching measurement · score 0.16
- body height · score 0.12
- hypothyroidism · score 0.12
- diabetes mellitus · score 0.11
- heel bone mineral density · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86SX3-F1 | alphafold | PREDICTED | 62.03 | — |
Amino-acid sequence (495 residues)
MGRRRQRVDP AAGARAGALP EAIAALSRSL PSGPSPEIFR RAKFDRPEAT SALWQLLFRV LSPLPAGNAL ASLALEVQAR LVKSALCSQG YPRLALAQLP EDGSQGSREL LLALSWLLAR GPVPEQMLAQ ARVPLGDEMT VCQCEALASP GPPAPHMEAE GPVDVRHVQW LMGKLRFRWR QLVSSQQEQC ALLSKIHLYT RGCHSDQSLS HLSVTEAEML RDPEGGQQVS GAGAAQNLDL AYPKCLHSFC TPGMGPRTFW NDLWLVCEQP GLLPGDWAAP LDPGGASACS LLSPFRALLR TLERENQRLE AVLAWRRSEL VFWRWMDTVL GTCAPEVPAA ASQPTFLPWV PERGGGELDL VVRELQALEE ELREAAERRR AAWEAKAGGC GRGPEWSAAR RASREAVEKE LGALQQCWER DGGPAQPHGP HRLVRREDGA AGDRDLRAAV VIRTLRSQEA CLEAVLRRLQ GQCRQELARL VGARPGLIWI PPPGR
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