About Trafficking protein particle complex subunit 6B
Trafficking protein particle complex subunit 6B (TRAPPC6B) is a protein
from Homo sapiens identified by UniProt accession
Q86SZ2, 158 residues long.
MolForge cross-references it against 0 known binders and
26 disease associations.
Target properties
| Protein name | Trafficking protein particle complex subunit 6B |
|---|
| UniProt accession | Q86SZ2 |
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| Gene | TRAPPC6B |
|---|
| Organism | Homo sapiens |
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| Length | 158 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (26)
Diseases linked to this target (Open Targets).
- neurodevelopmental disorder with microcephaly, epilepsy, and brain atrophy · score 0.64
- genetic disorder · score 0.33
- neurodegenerative disease · score 0.26
- self reported educational attainment · score 0.13
- vitamin D measurement · score 0.10
- lymphocyte count · score 0.08
- blood pressure · score 0.06
- platelet component distribution width · score 0.04
- gut microbiome measurement · score 0.04
- hypertension · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86SZ2-F1 | alphafold | PREDICTED | 92.76 | — |
Amino-acid sequence (158 residues)
MADEALFLLL HNEMVSGVYK SAEQGEVENG RCITKLENMG FRVGQGLIER FTKDTARFKD ELDIMKFICK DFWTTVFKKQ IDNLRTNHQG IYVLQDNKFR LLTQMSAGKQ YLEHASKYLA FTCGLIRGGL SNLGIKSIVT AEVSSMPACK FQVMIQKL
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