Small integral membrane protein 29 (SMIM29)

About Small integral membrane protein 29

Small integral membrane protein 29 (SMIM29) is a protein from Homo sapiens identified by UniProt accession Q86T20, 102 residues long. MolForge cross-references it against 0 known binders and 76 disease associations.

Target properties

Protein name	Small integral membrane protein 29
UniProt accession	Q86T20
Gene	SMIM29
Organism	Homo sapiens
Length	102 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (76)

Diseases linked to this target (Open Targets).

body height · score 0.53
BMI-adjusted waist circumference · score 0.37
body weights and measures · score 0.34
smoking behavior · score 0.33
mean corpuscular volume · score 0.33
reticulocyte count · score 0.32
lean body mass · score 0.31
BMI-adjusted waist-hip ratio · score 0.31
physical activity measurement · score 0.28
blood phosphate measurement · score 0.27

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q86T20-F1	alphafold	PREDICTED	72.03	—

Amino-acid sequence (102 residues)

MSNTTVPNAP QANSDSMVGY VLGPFFLITL VGVVVAVVMY VQKKKRVDRL RHHLLPMYSY DPAEELHEAE QELLSDMGDP KVVHGWQSGY QHKRMPLLDV KT

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards