About Zinc finger protein 605
Zinc finger protein 605 (ZNF605) is a protein
from Homo sapiens identified by UniProt accession
Q86T29, 641 residues long.
MolForge cross-references it against 0 known binders and
17 disease associations.
Target properties
| Protein name | Zinc finger protein 605 |
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| UniProt accession | Q86T29 |
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| Gene | ZNF605 |
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| Organism | Homo sapiens |
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| Length | 641 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (17)
Diseases linked to this target (Open Targets).
- mean corpuscular hemoglobin concentration · score 0.31
- mean corpuscular hemoglobin · score 0.25
- mean corpuscular volume · score 0.23
- cardiovascular disease · score 0.06
- hypertension · score 0.05
- waist-hip ratio · score 0.05
- BMI-adjusted waist-hip ratio · score 0.04
- cortical thickness · score 0.04
- intraocular pressure measurement · score 0.03
- cortical surface area measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86T29-F1 | alphafold | PREDICTED | 74.03 | — |
Amino-acid sequence (641 residues)
MIQSQISFED VAVDFTLEEW QLLNPTQKNL YRDVMLENYS NLVFLEVWLD NPKMWLRDNQ DNLKSMERGH KYDVFGKIFN SSINIVHVGL RSHKCGTGEK SLKCPFDLLI PKNNCERKKI DELNKKLLFC IKPGRTHGGI KYCDCSTCRK SSNEEPWLTA NHITHTGVYL CMECGRFFNK KSQLVIHQRT HTGEKPYQCS ECGKAFSQKS LLTVHQRTHS GEKPHGCSEC QKAFSRKSLL ILHQRIHTGE KPYGCSECGK AFSRKSQLKR HQITHTIEKP YSCSECGKAF SQKLKLITHQ RAHTGEKPYP CSHCGKAFFW KSQLITHQRT HTGKKPYGCG ECQKAFSRNS LLIRHQRIHT GEKPYECNEC GEAFIRKPQL IKHQITHTGE KNYRCSDCEE AFFKKSELIR HQKIHLGEKP YGCIQCGKTF FGKSQLLTHH RTHTGEKPYE CSECGKAFTQ KSSLISHQRT HTGEKPYECS ECRKTFSEKS SLIHHQRTHT GEKPFECSEC RKAFAWKPQL LRHQRIHTGE KPYECSECGK AFVQKVQLIK HQRNHTGEKT YGCSDCAKAF FEKAQLIIHQ RIHTGERPYK CGECGKSFTR KSHLMRHQRI HTGDKYYGCN ECGTTFNRKS QLMIHQRNHI I
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