About NBPF family member NBPF11
NBPF family member NBPF11 (NBPF11) is a protein
from Homo sapiens identified by UniProt accession
Q86T75, 865 residues long.
MolForge cross-references it against 0 known binders and
8 disease associations.
Target properties
| Protein name | NBPF family member NBPF11 |
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| UniProt accession | Q86T75 |
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| Gene | NBPF11 |
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| Organism | Homo sapiens |
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| Length | 865 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (8)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.29
- Ataxia-telangiectasia · score 0.01
- acute myeloid leukemia · score 0.00
- Macrocephaly · score 0.00
- Microcephaly · score 0.00
- glioblastoma multiforme · score 0.00
- congenital hypothyroidism · score 0.00
- neuroblastoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86T75-F1 | alphafold | PREDICTED | 49.40 | — |
Amino-acid sequence (865 residues)
MVVSAGPWSS EKAEMNILEI NEKLRPQLAE NKQQFRNLKE RCFLTQLAGF LANRQKKYKY EECKDLIKFM LRNERQFKEE KLAEQLKQAE ELRQYKVLVH SQERELTQLR EKLREGRDAS RSLNEHLQAL LTPDEPDKSQ GQDLQEQLAE GCRLAQHLVQ KLSPENDEDE DEDVQVEEDE KVLESSAPRE VQKAEESKVP EDSLEECAIT CSNSHGPCDS IQPHKNIKIT FEEDKVNSSL VVDRESSHDG CQDALNILPV PGPTSSATNV SMVVSAGPLS SEKAEMNILE INEKLCPQLA EKKQQFRSLK EKCFVTQVAC FLAKQQNKYK YEECKDLIKS MLRNERQFKE EKLAEQLKQA EELRQYKVLV HSQERELTQL REKLREGRDA SRSLNEHLQA LLTPDEPDKS QGQDLQEQLA EGCRLAQHLV QKLSPENDND DDEDVQVEVA EKVQKSSSPR EMQKAEEKEV PEDSLEECAI TCSNSHGPYD SNQPHRKTKI TFEEDKVDST LIGSSSHVEW EDAVHIIPEN ESDDEEEEEK GPVSPRNLQE SEEEEVPQES WDEGYSTLSI PPERLASYQS YSSTFHSLEE QQVCMAVDIG RHRWDQVKKE DQEATGPRLS RELLDEKEPE VLQDSLDRCY STPSVYLGLT DSCQPYRSAF YVLEQQRIGL AVDMDEIEKY QEVEEDQDPS CPRLSRELLA EKEPEVLQDS LDRCYSTPSG YLELPDLGQP YRSAVYSLEE QYLGLALDVD RIKKDQEEEE DQGPPCPRLS RELLEVVEPE VLQDSLDVIQ LLPVVLNSLT PASPTEVPFM HWRKNMLAFL LTWEKLKRRG RGRKEGEEDQ RRKEEGEEKK GKKIKTHHAP GSAAC
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