About MOB kinase activator 3B
MOB kinase activator 3B (MOB3B) is a protein
from Homo sapiens identified by UniProt accession
Q86TA1, 216 residues long.
MolForge cross-references it against 0 known binders and
41 disease associations.
Target properties
| Protein name | MOB kinase activator 3B |
|---|
| UniProt accession | Q86TA1 |
|---|
| Gene | MOB3B |
|---|
| Organism | Homo sapiens |
|---|
| Length | 216 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (41)
Diseases linked to this target (Open Targets).
- amyotrophic lateral sclerosis · score 0.50
- motor neuron disease · score 0.40
- body height · score 0.40
- Brain atrophy · score 0.34
- sporadic amyotrophic lateral sclerosis · score 0.34
- hair colour measurement · score 0.31
- blood protein measurement · score 0.22
- mean platelet volume · score 0.19
- body mass index · score 0.17
- lean body mass · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86TA1-F1 | alphafold | PREDICTED | 89.79 | — |
Amino-acid sequence (216 residues)
MSIALKQVFN KDKTFRPKRK FEPGTQRFEL HKRAQASLNS GVDLKAAVQL PSGEDQNDWV AVHVVDFFNR INLIYGTICE FCTERTCPVM SGGPKYEYRW QDDLKYKKPT ALPAPQYMNL LMDWIEVQIN NEEIFPTCVG VPFPKNFLQI CKKILCRLFR VFVHVYIHHF DRVIVMGAEA HVNTCYKHFY YFVTEMNLID RKELEPLKEM TSRMCH
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