About Transmembrane protein 150A
Transmembrane protein 150A (TMEM150A) is a protein
from Homo sapiens identified by UniProt accession
Q86TG1, 271 residues long.
MolForge cross-references it against 0 known binders and
26 disease associations.
Target properties
| Protein name | Transmembrane protein 150A |
|---|
| UniProt accession | Q86TG1 |
|---|
| Gene | TMEM150A |
|---|
| Organism | Homo sapiens |
|---|
| Length | 271 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (26)
Diseases linked to this target (Open Targets).
- lean body mass · score 0.22
- leukocyte count · score 0.19
- body height · score 0.17
- appendicular lean mass · score 0.10
- fat body mass · score 0.09
- whole body water mass · score 0.08
- base metabolic rate measurement · score 0.07
- glioblastoma multiforme · score 0.07
- platelet count · score 0.07
- lymphocyte count · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86TG1-F1 | alphafold | PREDICTED | 89.69 | — |
Amino-acid sequence (271 residues)
MTAWILLPVS LSAFSITGIW TVYAMAVMNH HVCPVENWSY NESCPPDPAE QGGPKTCCTL DDVPLISKCG SYPPESCLFS LIGNMGAFMV ALICLLRYGQ LLEQSRHSWV NTTALITGCT NAAGLLVVGN FQVDHARSLH YVGAGVAFPA GLLFVCLHCA LSYQGATAPL DLAVAYLRSV LAVIAFITLV LSGVFFVHES SQLQHGAALC EWVCVIDILI FYGTFSYEFG AVSSDTLVAA LQPTPGRACK SSGSSSTSTH LNCAPESIAM I
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