WD repeat-containing protein 86 (WDR86)

About WD repeat-containing protein 86

WD repeat-containing protein 86 (WDR86) is a protein from Homo sapiens identified by UniProt accession Q86TI4, 376 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.

Target properties

Protein name	WD repeat-containing protein 86
UniProt accession	Q86TI4
Gene	WDR86
Organism	Homo sapiens
Length	376 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (17)

Diseases linked to this target (Open Targets).

heel bone mineral density · score 0.30
protein measurement · score 0.28
Abnormality of refraction · score 0.23
platelet crit · score 0.09
body height · score 0.03
breast carcinoma · score 0.01
neoplasm · score 0.01
preeclampsia · score 0.01
cancer · score 0.00
invasive breast ductal carcinoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q86TI4-F1	alphafold	PREDICTED	90.35	—

Amino-acid sequence (376 residues)

MGGGGSALRV CADHRGGINW LSLSPDGQRL LTGSEDGTAR LWSTADGQCC ALLQGHESYV TFCQLEDEAA FTCSADCTIR RWDVLTGQCL QVYRGHTSIV NRILVANNQL FSSSYDRTAR VWSVDKGQMS REFRGHRNCV LTLAYSAPWD LPSTPCAEEA AAGGLLVTGS TDGTAKVWQV ASGCCHQTLR GHTGAVLCLV LDTPGHTAFT GSTDATIRAW DILSGEQLRV FREHRGSVIC LELVNRLVYS GSADRTVKCW LADTGECVRT FTAHRRNVSA LKYHAGTLFT GSGDACARAF DAQSGELRRV FRGHTFIINC IQVHGQVLYT ASHDGALRLW DVRGLRGAPR PPPPMRSLSR LFSNKVGCAA APLQPA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards