Zinc finger protein 554 (ZNF554)

About Zinc finger protein 554

Zinc finger protein 554 (ZNF554) is a protein from Homo sapiens identified by UniProt accession Q86TJ5, 538 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.

Target properties

Protein name	Zinc finger protein 554
UniProt accession	Q86TJ5
Gene	ZNF554
Organism	Homo sapiens
Length	538 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (16)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.39
sex hormone-binding globulin measurement · score 0.16
low density lipoprotein cholesterol measurement · score 0.14
platelet count · score 0.13
total cholesterol measurement · score 0.13
genetic disorder · score 0.12
testosterone measurement · score 0.11
platelet crit · score 0.08
preeclampsia · score 0.06
neoplasm · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q86TJ5-F1	alphafold	PREDICTED	55.49	—

Amino-acid sequence (538 residues)

MVTCAHLGRR ARLPAAQPSA CPGTCFSQEE RMAAGYLPRW SQELVTFEDV SMDFSQEEWE LLEPAQKNLY REVMLENYRN VVSLEALKNQ CTDVGIKEGP LSPAQTSQVT SLSSWTGYLL FQPVASSHLE QREALWIEEK GTPQASCSDW MTVLRNQDST YKKVALQEEP ASGINMIKLI REDGGWKQLE DSHEDPQGLL SQKASLHVVA VPQEKATAWH GFGENGNLSP ALVLSQGSSK GNHLCGSELD ITSLASDSVL NHHQLGYADR RPCESNECGN AIRQNSHFIQ HGGKMFVYLE NGQSLNHGMA LTIHNKINTA EKPFECHQCG KVFNRRHSLS EHQRIHTGEK PYECQECGRA FTHSSTLTRH LRTHTGEKPY GCGECGKAFN RISSLTQHQR IHTGEKPYKC EDCGKSFCQS SYLILHKRTH TGEKPYECSE CGKAFSDRSS LNQHERTHTG ENPYECKQCG RAFSQRSSLV RHERTHTGEK PYRCQECGKA FSQSSSLVTH QKTHSSQKTY KIIDCGKAFY QNRHLIGY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards