tRNA 2'-phosphotransferase 1 (TRPT1)

About tRNA 2'-phosphotransferase 1

tRNA 2'-phosphotransferase 1 (TRPT1) is a protein from Homo sapiens identified by UniProt accession Q86TN4, 253 residues long. MolForge cross-references it against 0 known binders and 35 disease associations.

Target properties

Protein name	tRNA 2'-phosphotransferase 1
UniProt accession	Q86TN4
Gene	TRPT1
Organism	Homo sapiens
Length	253 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q86TN4-F1	alphafold	PREDICTED	85.67	—

Amino-acid sequence (253 residues)

MNFSGGGRQE AAGSRGRRAP RPREQDRDVQ LSKALSYALR HGALKLGLPM GADGFVPLGT LLQLPQFRGF SAEDVQRVVD TNRKQRFALQ LGDPSTGLLI RANQGHSLQV PKLELMPLET PQALPPMLVH GTFWKHWPSI LLKGLSCQGR THIHLAPGLP GDPGIISGMR SHCEIAVFID GPLALADGIP FFRSANGVIL TPGNTDGFLL PKYFKEALQL RPTRKPLSLA GDEETECQSS PKHSSRERRR IQQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards