Exopolyphosphatase PRUNE1 (PRUNE1)

About Exopolyphosphatase PRUNE1

Exopolyphosphatase PRUNE1 (PRUNE1) is a protein from Homo sapiens identified by UniProt accession Q86TP1, 453 residues long. MolForge cross-references it against 0 known binders and 80 disease associations.

Target properties

Protein name	Exopolyphosphatase PRUNE1
UniProt accession	Q86TP1
Gene	PRUNE1
Organism	Homo sapiens
Length	453 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (1)

DrugCentral-linked approved drugs that act on this protein.

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q86TP1-F1	alphafold	PREDICTED	85.23	—

Amino-acid sequence (453 residues)

MEDYLQGCRA ALQESRPLHV VLGNEACDLD STVSALALAF YLAKTTEAEE VFVPVLNIKR SELPLRGDIV FFLQKVHIPE SILIFRDEID LHALYQAGQL TLILVDHHIL SKSDTALEEA VAEVLDHRPI EPKHCPPCHV SVELVGSCAT LVTERILQGA PEILDRQTAA LLHGTIILDC VNMDLKIGKA TPKDSKYVEK LEALFPDLPK RNDIFDSLQK AKFDVSGLTT EQMLRKDQKT IYRQGVKVAI SAIYMDLEAF LQRSNLLADL HAFCQAHSYD VLVAMTIFFN THNEPVRQLA IFCPHVALQT TICEVLERSH SPPLKLTPAS STHPNLHAYL QGNTQVSRKK LLPLLQEALS AYFDSMKIPS GQPETADVSR EQVDKELDRA SNSLISGLSQ DEEDPPLPPT PMNSLVDECP LDQGLPKLSA EAVFEKCSQI SLSQSTTASL SKK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards