Large ribosomal subunit protein mL52 (MRPL52)

About Large ribosomal subunit protein mL52

Large ribosomal subunit protein mL52 (MRPL52) is a protein from Homo sapiens identified by UniProt accession Q86TS9, 123 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.

Target properties

Protein name	Large ribosomal subunit protein mL52
UniProt accession	Q86TS9
Gene	MRPL52
Organism	Homo sapiens
Length	123 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (22)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.51
base metabolic rate measurement · score 0.11
lean body mass · score 0.08
breast cancer · score 0.07
Palmar Fibromatosis · score 0.07
Fasciitis · score 0.07
HbA1c measurement · score 0.07
fat body mass · score 0.06
prostate carcinoma · score 0.06
whole body water mass · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q86TS9-F1	alphafold	PREDICTED	85.49	—

Amino-acid sequence (123 residues)

MAALGTVLFT GVRRLHCSVA AWAGGQWRLQ QGLAANPSGY GPLTELPDWS YADGRPAPPM KGQLRRKAER ETFARRVVLL SQEMDAGLQA WQLRQQKLQE EQRKQENALK PKGASLKSPL PSQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards