Probable RNA-binding protein 23 (RBM23)

About Probable RNA-binding protein 23

Probable RNA-binding protein 23 (RBM23) is a protein from Homo sapiens identified by UniProt accession Q86U06, 439 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.

Target properties

Protein name	Probable RNA-binding protein 23
UniProt accession	Q86U06
Gene	RBM23
Organism	Homo sapiens
Length	439 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (25)

Diseases linked to this target (Open Targets).

self reported educational attainment · score 0.19
mathematical ability · score 0.19
intelligence · score 0.17
FEV/FVC ratio · score 0.16
cup-to-disc ratio measurement · score 0.15
blood phosphate measurement · score 0.15
systolic blood pressure · score 0.14
eosinophil count · score 0.14
schizophrenia · score 0.13
brain measurement · score 0.13

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q86U06-F1	alphafold	PREDICTED	63.90	—

Amino-acid sequence (439 residues)

MASDDFDIVI EAMLEAPYKK EEDEQQRKEV KKDYPSNTTS STSNSGNETS GSSTIGETSK KKRSRSHNKS RDRKRSRSRD RDRYRRRNSR SRSPGRQCRH RSRSWDRRHG SESRSRDHRR EDRVHYRSPP LATGYRYGHS KSPHFREKSP VREPVDNLSP EERDARTVFC MQLAARIRPR DLEDFFSAVG KVRDVRIISD RNSRRSKGIA YVEFCEIQSV PLAIGLTGQR LLGVPIIVQA SQAEKNRLAA MANNLQKGNG GPMRLYVGSL HFNITEDMLR GIFEPFGKID NIVLMKDSDT GRSKGYGFIT FSDSECARRA LEQLNGFELA GRPMRVGHVT ERLDGGTDIT FPDGDQELDL GSAGGRFQLM AKLAEGAGIQ LPSTAAAAAA AAAQAAALQL NGAVPLGALN PAALTALSPA LNLASQCFQL SSLFTPQTM

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards