About RPA-interacting protein
RPA-interacting protein (RPAIN) is a protein
from Homo sapiens identified by UniProt accession
Q86UA6, 219 residues long.
MolForge cross-references it against 0 known binders and
51 disease associations.
Target properties
| Protein name | RPA-interacting protein |
|---|
| UniProt accession | Q86UA6 |
|---|
| Gene | RPAIN |
|---|
| Organism | Homo sapiens |
|---|
| Length | 219 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (51)
Diseases linked to this target (Open Targets).
- body mass index · score 0.31
- age at menopause · score 0.30
- leukocyte count · score 0.28
- neurodegenerative disease · score 0.25
- platelet count · score 0.23
- body fat percentage · score 0.15
- sex hormone-binding globulin measurement · score 0.15
- myeloid white cell count · score 0.15
- body weight · score 0.13
- serum alanine aminotransferase measurement · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86UA6-F1 | alphafold | PREDICTED | 81.88 | — |
Amino-acid sequence (219 residues)
MAESLRSPRR SLYKLVGSPP WKEAFRQRCL ERMRNSRDRL LNRYRQAGSS GPGNSQNSFL VQEVMEEEWN ALQSVENCPE DLAQLEELID MAVLEEIQQE LINQEQSIIS EYEKSLQFDE KCLSIMLAEW EANPLICPVC TKYNLRITSG VVVCQCGLSI PSHSSELTEQ KLRACLEGSI NEHSAHCPHT PEFSVTGGTE EKSSLLMSCL ACDTWAVIL
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