About Basic immunoglobulin-like variable motif-containing protein
Basic immunoglobulin-like variable motif-containing protein (BIVM) is a protein
from Homo sapiens identified by UniProt accession
Q86UB2, 503 residues long.
MolForge cross-references it against 0 known binders and
133 disease associations.
Target properties
| Protein name | Basic immunoglobulin-like variable motif-containing protein |
|---|
| UniProt accession | Q86UB2 |
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| Gene | BIVM |
|---|
| Organism | Homo sapiens |
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| Length | 503 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (133)
Diseases linked to this target (Open Targets).
- apolipoprotein A 1 measurement · score 0.08
- Blackfan-Diamond anemia · score 0.08
- dermatitis herpetiformis, familial · score 0.07
- PHF-tau measurement · score 0.07
- MODY · score 0.06
- primary familial polycythemia due to EPO receptor mutation · score 0.06
- beta-thalassemia-X-linked thrombocytopenia syndrome · score 0.06
- hereditary persistence of fetal hemoglobin-sickle cell disease syndrome · score 0.06
- alpha-thalassemia-myelodysplastic syndrome · score 0.06
- C-reactive protein measurement · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86UB2-F1 | alphafold | PREDICTED | 65.83 | — |
Amino-acid sequence (503 residues)
MPNVAETERS NDSGNGEHKS ERKSPEENLQ GAVKSFCTSA SGAPLGPKGD GHYPWSCPVT HTREKIYAIC SDYAFLNQAT SIYKTPNPSR SPCLPDSTSL SAGNNSSRYI GIPTSTSEII YNEENSLENL SNSLGKLPLA WEIDKSEFDG VTTNSKHKSG NAKKQVSKRK TSDKKGRYQK ECPQHSPLED IKQRKVLDLR RWYCISRPQY KTSCGISSLI SCWNFLYSTM GAGNLPPITQ EEALHILGFQ PPFEDIRFGP FTGNTTLMRW FRQINDHFHV KGCSYVLYKP HGKNKTAGET ASGALSKLTR GLKDESLAYI YHCQNHYFCP IGFEATPVKA NKAFSRGPLS PQEVEYWILI GESSRKHPAI HCKKWADIVT DLNTQNPEYL DIRHLERGLQ YRKTKKVGGN LHCIIAFQRL NWQRFGLWNF PFGTIRQESQ PPTHAQGIAK SESEDNISKK QHGRLGRSFS ASFHQDSAWK KMSSIHERRN SGYQGYSDYD GND
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