About Out at first protein homolog
Out at first protein homolog (OAF) is a protein
from Homo sapiens identified by UniProt accession
Q86UD1, 273 residues long.
MolForge cross-references it against 0 known binders and
30 disease associations.
Target properties
| Protein name | Out at first protein homolog |
|---|
| UniProt accession | Q86UD1 |
|---|
| Gene | OAF |
|---|
| Organism | Homo sapiens |
|---|
| Length | 273 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (30)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.34
- interleukin 25 measurement · score 0.22
- vitamin D measurement · score 0.19
- systolic blood pressure · score 0.17
- protein measurement · score 0.17
- urate measurement · score 0.10
- diastolic blood pressure · score 0.09
- IGF-1 measurement · score 0.08
- serum urea measurement · score 0.08
- mean arterial pressure · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86UD1-F1 | alphafold | PREDICTED | 87.41 | — |
Amino-acid sequence (273 residues)
MRLPGVPLAR PALLLLLPLL APLLGTGAPA ELRVRVRLPD GQVTEESLQA DSDADSISLE LRKPDGTLVS FTADFKKDVK VFRALILGEL EKGQSQFQAL CFVTQLQHNE IIPSEAMAKL RQKNPRAVRQ AEEVRGLEHL HMDVAVNFSQ GALLSPHLHN VCAEAVDAIY TRQEDVRFWL EQGVDSSVFE ALPKASEQAE LPRCRQVGDH GKPCVCRYGL SLAWYPCMLK YCHSRDRPTP YKCGIRSCQK SYSFDFYVPQ RQLCLWDEDP YPG
Explore Out at first protein homolog with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets