TBC1 domain family member 26 (TBC1D26)

About TBC1 domain family member 26

TBC1 domain family member 26 (TBC1D26) is a protein from Homo sapiens identified by UniProt accession Q86UD7, 250 residues long. MolForge cross-references it against 0 known binders and 2 disease associations.

Target properties

Protein name	TBC1 domain family member 26
UniProt accession	Q86UD7
Gene	TBC1D26
Organism	Homo sapiens
Length	250 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (2)

Diseases linked to this target (Open Targets).

cancer · score 0.01
cutaneous melanoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q86UD7-F1	alphafold	PREDICTED	75.76	—

Amino-acid sequence (250 residues)

MEMDGDPYNL PAQGQGNIII TKYEQGHRAG AAVDLGHEQV DVRKYTNNLG IVHEMELPHV SALEVKQRRK ESKRTNKWQK MLADWTKYRS TKKLSQRVYK VIPLAVRGRA WSLLLDIDRI KSQNPGKYKV MKEKGKRSSR IIHCIQLDVS HTLQKHMMFI QRFGVKQQEL CDILVAYSAY NPEVGYHRDL SRITAILLLC LPEEDAFWAL TQLLAGERHS LWYSTAQILP GSRGSYRTRS RCCTSPSQRS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards