About Solute carrier organic anion transporter family member 6A1
Solute carrier organic anion transporter family member 6A1 (SLCO6A1) is a protein
from Homo sapiens identified by UniProt accession
Q86UG4, 719 residues long.
MolForge cross-references it against 0 known binders and
50 disease associations.
Target properties
| Protein name | Solute carrier organic anion transporter family member 6A1 |
|---|
| UniProt accession | Q86UG4 |
|---|
| Gene | SLCO6A1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 719 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (50)
Diseases linked to this target (Open Targets).
- schizophrenia · score 0.28
- body height · score 0.27
- BMI-adjusted waist circumference · score 0.26
- diastolic blood pressure · score 0.26
- BMI-adjusted waist-hip ratio · score 0.23
- Crohn's disease · score 0.23
- mean arterial pressure · score 0.21
- diabetes mellitus · score 0.11
- glucose measurement · score 0.06
- cytokine measurement · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q86UG4-F1 | alphafold | PREDICTED | 76.71 | — |
Amino-acid sequence (719 residues)
MFVGVARHSG SQDEVSRGVE PLEAARAQPA KDRRAKGTPK SSKPGKKHRY LRLLPEALIR FGGFRKRKKA KSSVSKKPGE VDDSLEQPCG LGCLVSTCCE CCNNIRCFMI FYCILLICQG VVFGLIDVSI GDFQKEYQLK TIEKLALEKS YDISSGLVAI FIAFYGDRKK VIWFVASSFL IGLGSLLCAF PSINEENKQS KVGIEDICEE IKVVSGCQSS GISFQSKYLS FFILGQTVQG IAGMPLYILG ITFIDENVAT HSAGIYLGIA ECTSMIGYAL GYVLGAPLVK VPENTTSATN TTVNNGSPEW LWTWWINFLF AAVVAWCTLI PLSCFPNNMP GSTRIKARKR KQLHFFDSRL KDLKLGTNIK DLCAALWILM KNPVLICLAL SKATEYLVII GASEFLPIYL ENQFILTPTV ATTLAGLVLI PGGALGQLLG GVIVSTLEMS CKALMRFIMV TSVISLILLV FIIFVRCNPV QFAGINEDYD GTGKLGNLTA PCNEKCRCSS SIYSSICGRD DIEYFSPCFA GCTYSKAQNQ KKMYYNCSCI KEGLITADAE GDFIDARPGK CDAKCYKLPL FIAFIFSTLI FSGFSGVPIV LAMTRVVPDK LRSLALGVSY VILRIFGTIP GPSIFKMSGE TSCILRDVNK CGHTGRCWIY NKTKMAFLLV GICFLCKLCT IIFTTIAFFI YKRRLNENTD FPDVTVKNPK VKKKEETDL
Explore Solute carrier organic anion transporter family member 6A1 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets